Detection of Ultra-Rare ESR1 Mutations in Primary Breast Cancer Using LNA-Clamp ddPCR

SIMPLE SUMMARY: ESR1 mutations in breast cancer are one of the mechanisms of resistance to aromatase inhibitors (AI). These mutations are common in metastatic breast cancer (MBC). In past reports, mutations in primary tumors were so rare that they were thought to occur de novo with AI therapy. Conve...

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Detalles Bibliográficos
Autores principales: Hashimoto, Yoko, Masunaga, Nanae, Kagara, Naofumi, Abe, Kaori, Yoshinami, Tetsuhiro, Tsukabe, Masami, Sota, Yoshiaki, Miyake, Tomohiro, Tanei, Tomonori, Shimoda, Masafumi, Shimazu, Kenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177270/
https://www.ncbi.nlm.nih.gov/pubmed/37174098
http://dx.doi.org/10.3390/cancers15092632

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