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Magnetic Resonance Imaging Features of Rhino-Orbito-Cerebral Mucormycosis in Post-COVID-19 Patients: Radio-Pathological Correlation
There has been a notable increase in rhino-orbito-cerebral mucormycosis (ROCM) post-coronavirus disease 2019 (COVID-19), which is an invasive fungal infection with a fatal outcome. Magnetic resonance imaging (MRI) is a valuable tool for early diagnosis of ROCM and assists in the proper management of...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177362/ https://www.ncbi.nlm.nih.gov/pubmed/37174937 http://dx.doi.org/10.3390/diagnostics13091546 |
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author | Hassan, Rania Mostafa Almalki, Yassir Edrees Basha, Mohammad Abd Alkhalik Gobran, Mai Ahmed Alqahtani, Saad Misfer Assiri, Abdullah M. Alqahtani, Saeed Alduraibi, Sharifa Khalid Aboualkheir, Mervat Almushayti, Ziyad A. Aldhilan, Asim S. Aly, Sameh Abdelaziz Alshamy, Asmaa A. |
author_facet | Hassan, Rania Mostafa Almalki, Yassir Edrees Basha, Mohammad Abd Alkhalik Gobran, Mai Ahmed Alqahtani, Saad Misfer Assiri, Abdullah M. Alqahtani, Saeed Alduraibi, Sharifa Khalid Aboualkheir, Mervat Almushayti, Ziyad A. Aldhilan, Asim S. Aly, Sameh Abdelaziz Alshamy, Asmaa A. |
author_sort | Hassan, Rania Mostafa |
collection | PubMed |
description | There has been a notable increase in rhino-orbito-cerebral mucormycosis (ROCM) post-coronavirus disease 2019 (COVID-19), which is an invasive fungal infection with a fatal outcome. Magnetic resonance imaging (MRI) is a valuable tool for early diagnosis of ROCM and assists in the proper management of these cases. This study aimed to describe the characteristic MRI findings of ROCM in post-COVID-19 patients to help in the early diagnosis and management of these patients. This retrospective descriptive study was conducted at a single hospital and included 52 patients with COVID-19 and a histopathologically proven ROCM infection who were referred for an MRI of the paranasal sinuses (PNS) due to sino-orbital manifestations. Two radiologists reviewed all the MR images in consensus. The diagnosis was confirmed by histopathological examination. The maxillary sinus was the most commonly affected PNS (96.2%). In most patients (57.7%), multiple sinuses were involved with the black turbinate sign on postcontrast images. Extrasinus was evident in 43 patients with orbital involvement. The pterygopalatine fossa was involved in four patients. Three patients had cavernous sinus extension, two had pachymeningeal enhancement, and one had epidural collection. The alveolar margin was affected in two patients, and five patients had an extension to the cheek. The awareness of radiologists by the characteristic MRI features of ROCM in post-COVID-19 patients helps in early detection, early proper management, and prevention of morbid complications. |
format | Online Article Text |
id | pubmed-10177362 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-101773622023-05-13 Magnetic Resonance Imaging Features of Rhino-Orbito-Cerebral Mucormycosis in Post-COVID-19 Patients: Radio-Pathological Correlation Hassan, Rania Mostafa Almalki, Yassir Edrees Basha, Mohammad Abd Alkhalik Gobran, Mai Ahmed Alqahtani, Saad Misfer Assiri, Abdullah M. Alqahtani, Saeed Alduraibi, Sharifa Khalid Aboualkheir, Mervat Almushayti, Ziyad A. Aldhilan, Asim S. Aly, Sameh Abdelaziz Alshamy, Asmaa A. Diagnostics (Basel) Article There has been a notable increase in rhino-orbito-cerebral mucormycosis (ROCM) post-coronavirus disease 2019 (COVID-19), which is an invasive fungal infection with a fatal outcome. Magnetic resonance imaging (MRI) is a valuable tool for early diagnosis of ROCM and assists in the proper management of these cases. This study aimed to describe the characteristic MRI findings of ROCM in post-COVID-19 patients to help in the early diagnosis and management of these patients. This retrospective descriptive study was conducted at a single hospital and included 52 patients with COVID-19 and a histopathologically proven ROCM infection who were referred for an MRI of the paranasal sinuses (PNS) due to sino-orbital manifestations. Two radiologists reviewed all the MR images in consensus. The diagnosis was confirmed by histopathological examination. The maxillary sinus was the most commonly affected PNS (96.2%). In most patients (57.7%), multiple sinuses were involved with the black turbinate sign on postcontrast images. Extrasinus was evident in 43 patients with orbital involvement. The pterygopalatine fossa was involved in four patients. Three patients had cavernous sinus extension, two had pachymeningeal enhancement, and one had epidural collection. The alveolar margin was affected in two patients, and five patients had an extension to the cheek. The awareness of radiologists by the characteristic MRI features of ROCM in post-COVID-19 patients helps in early detection, early proper management, and prevention of morbid complications. MDPI 2023-04-25 /pmc/articles/PMC10177362/ /pubmed/37174937 http://dx.doi.org/10.3390/diagnostics13091546 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Hassan, Rania Mostafa Almalki, Yassir Edrees Basha, Mohammad Abd Alkhalik Gobran, Mai Ahmed Alqahtani, Saad Misfer Assiri, Abdullah M. Alqahtani, Saeed Alduraibi, Sharifa Khalid Aboualkheir, Mervat Almushayti, Ziyad A. Aldhilan, Asim S. Aly, Sameh Abdelaziz Alshamy, Asmaa A. Magnetic Resonance Imaging Features of Rhino-Orbito-Cerebral Mucormycosis in Post-COVID-19 Patients: Radio-Pathological Correlation |
title | Magnetic Resonance Imaging Features of Rhino-Orbito-Cerebral Mucormycosis in Post-COVID-19 Patients: Radio-Pathological Correlation |
title_full | Magnetic Resonance Imaging Features of Rhino-Orbito-Cerebral Mucormycosis in Post-COVID-19 Patients: Radio-Pathological Correlation |
title_fullStr | Magnetic Resonance Imaging Features of Rhino-Orbito-Cerebral Mucormycosis in Post-COVID-19 Patients: Radio-Pathological Correlation |
title_full_unstemmed | Magnetic Resonance Imaging Features of Rhino-Orbito-Cerebral Mucormycosis in Post-COVID-19 Patients: Radio-Pathological Correlation |
title_short | Magnetic Resonance Imaging Features of Rhino-Orbito-Cerebral Mucormycosis in Post-COVID-19 Patients: Radio-Pathological Correlation |
title_sort | magnetic resonance imaging features of rhino-orbito-cerebral mucormycosis in post-covid-19 patients: radio-pathological correlation |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177362/ https://www.ncbi.nlm.nih.gov/pubmed/37174937 http://dx.doi.org/10.3390/diagnostics13091546 |
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