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Shining the Light on Astrocytic Ensembles
While neurons have traditionally been considered the primary players in information processing, the role of astrocytes in this mechanism has largely been overlooked due to experimental constraints. In this review, we propose that astrocytic ensembles are active working groups that contribute signifi...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177371/ https://www.ncbi.nlm.nih.gov/pubmed/37174653 http://dx.doi.org/10.3390/cells12091253 |
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author | Delgado, Laura Navarrete, Marta |
author_facet | Delgado, Laura Navarrete, Marta |
author_sort | Delgado, Laura |
collection | PubMed |
description | While neurons have traditionally been considered the primary players in information processing, the role of astrocytes in this mechanism has largely been overlooked due to experimental constraints. In this review, we propose that astrocytic ensembles are active working groups that contribute significantly to animal conduct and suggest that studying the maps of these ensembles in conjunction with neurons is crucial for a more comprehensive understanding of behavior. We also discuss available methods for studying astrocytes and argue that these ensembles, complementarily with neurons, code and integrate complex behaviors, potentially specializing in concrete functions. |
format | Online Article Text |
id | pubmed-10177371 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-101773712023-05-13 Shining the Light on Astrocytic Ensembles Delgado, Laura Navarrete, Marta Cells Review While neurons have traditionally been considered the primary players in information processing, the role of astrocytes in this mechanism has largely been overlooked due to experimental constraints. In this review, we propose that astrocytic ensembles are active working groups that contribute significantly to animal conduct and suggest that studying the maps of these ensembles in conjunction with neurons is crucial for a more comprehensive understanding of behavior. We also discuss available methods for studying astrocytes and argue that these ensembles, complementarily with neurons, code and integrate complex behaviors, potentially specializing in concrete functions. MDPI 2023-04-26 /pmc/articles/PMC10177371/ /pubmed/37174653 http://dx.doi.org/10.3390/cells12091253 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Delgado, Laura Navarrete, Marta Shining the Light on Astrocytic Ensembles |
title | Shining the Light on Astrocytic Ensembles |
title_full | Shining the Light on Astrocytic Ensembles |
title_fullStr | Shining the Light on Astrocytic Ensembles |
title_full_unstemmed | Shining the Light on Astrocytic Ensembles |
title_short | Shining the Light on Astrocytic Ensembles |
title_sort | shining the light on astrocytic ensembles |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177371/ https://www.ncbi.nlm.nih.gov/pubmed/37174653 http://dx.doi.org/10.3390/cells12091253 |
work_keys_str_mv | AT delgadolaura shiningthelightonastrocyticensembles AT navarretemarta shiningthelightonastrocyticensembles |