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Shining the Light on Astrocytic Ensembles

While neurons have traditionally been considered the primary players in information processing, the role of astrocytes in this mechanism has largely been overlooked due to experimental constraints. In this review, we propose that astrocytic ensembles are active working groups that contribute signifi...

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Detalles Bibliográficos
Autores principales: Delgado, Laura, Navarrete, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177371/
https://www.ncbi.nlm.nih.gov/pubmed/37174653
http://dx.doi.org/10.3390/cells12091253
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author Delgado, Laura
Navarrete, Marta
author_facet Delgado, Laura
Navarrete, Marta
author_sort Delgado, Laura
collection PubMed
description While neurons have traditionally been considered the primary players in information processing, the role of astrocytes in this mechanism has largely been overlooked due to experimental constraints. In this review, we propose that astrocytic ensembles are active working groups that contribute significantly to animal conduct and suggest that studying the maps of these ensembles in conjunction with neurons is crucial for a more comprehensive understanding of behavior. We also discuss available methods for studying astrocytes and argue that these ensembles, complementarily with neurons, code and integrate complex behaviors, potentially specializing in concrete functions.
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spelling pubmed-101773712023-05-13 Shining the Light on Astrocytic Ensembles Delgado, Laura Navarrete, Marta Cells Review While neurons have traditionally been considered the primary players in information processing, the role of astrocytes in this mechanism has largely been overlooked due to experimental constraints. In this review, we propose that astrocytic ensembles are active working groups that contribute significantly to animal conduct and suggest that studying the maps of these ensembles in conjunction with neurons is crucial for a more comprehensive understanding of behavior. We also discuss available methods for studying astrocytes and argue that these ensembles, complementarily with neurons, code and integrate complex behaviors, potentially specializing in concrete functions. MDPI 2023-04-26 /pmc/articles/PMC10177371/ /pubmed/37174653 http://dx.doi.org/10.3390/cells12091253 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Delgado, Laura
Navarrete, Marta
Shining the Light on Astrocytic Ensembles
title Shining the Light on Astrocytic Ensembles
title_full Shining the Light on Astrocytic Ensembles
title_fullStr Shining the Light on Astrocytic Ensembles
title_full_unstemmed Shining the Light on Astrocytic Ensembles
title_short Shining the Light on Astrocytic Ensembles
title_sort shining the light on astrocytic ensembles
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177371/
https://www.ncbi.nlm.nih.gov/pubmed/37174653
http://dx.doi.org/10.3390/cells12091253
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