Progerinin, an Inhibitor of Progerin, Alleviates Cardiac Abnormalities in a Model Mouse of Hutchinson–Gilford Progeria Syndrome

Hutchinson–Gilford Progeria Syndrome (HGPS) is an ultra-rare human premature aging disorder that precipitates death because of cardiac disease. Almost all cases of HGPS are caused by aberrant splicing of the LMNA gene that results in the production of a mutant Lamin A protein termed progerin. In our...

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Detalles Bibliográficos
Autores principales: Kang, So-mi, Seo, Seungwoon, Song, Eun Ju, Kweon, Okhee, Jo, Ah-hyeon, Park, Soyoung, Woo, Tae-Gyun, Kim, Bae-Hoon, Oh, Goo Taeg, Park, Bum-Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177486/
https://www.ncbi.nlm.nih.gov/pubmed/37174632
http://dx.doi.org/10.3390/cells12091232

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