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Influence of Adipose Tissue on Early Metabolic Programming: Conditioning Factors and Early Screening

Background: Obesity and being overweight have become one of the world’s most severe health issues, not only because of the pathology but also because of the development of related comorbidities. Even when children reach adulthood, the mother’s environment during pregnancy has been found to have a si...

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Autores principales: Puche-Juarez, Maria, Toledano, Juan M., Ochoa, Julio J., Diaz-Castro, Javier, Moreno-Fernandez, Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177621/
https://www.ncbi.nlm.nih.gov/pubmed/37174902
http://dx.doi.org/10.3390/diagnostics13091510
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author Puche-Juarez, Maria
Toledano, Juan M.
Ochoa, Julio J.
Diaz-Castro, Javier
Moreno-Fernandez, Jorge
author_facet Puche-Juarez, Maria
Toledano, Juan M.
Ochoa, Julio J.
Diaz-Castro, Javier
Moreno-Fernandez, Jorge
author_sort Puche-Juarez, Maria
collection PubMed
description Background: Obesity and being overweight have become one of the world’s most severe health issues, not only because of the pathology but also because of the development of related comorbidities. Even when children reach adulthood, the mother’s environment during pregnancy has been found to have a significant impact on obesity prevention in children. Thus, both maternal dietary habits and other factors such as gestational diabetes mellitus, excessive weight gain during pregnancy, smoking, or endocrine factors, among others, could influence newborn growth, adiposity, and body composition at birth, in childhood and adolescence, hence programming health in adulthood. Methods: The aim of this review is to analyze the most recent human studies on the programming of fetal adipose tissue to determine which modifiable factors may influence adiposity and thus prevent specific disorders later in life by means of a bibliographic review of articles related to the subject over the last ten years. Conclusions: The importance of a healthy diet and lifestyle not only during pregnancy and the first months of life but also throughout childhood, especially during the first two years of life as this is a period of great plasticity, where the foundations for optimal health in later life will be laid, preventing the emergence of noncommunicable diseases including obesity, diabetes mellitus type 2, hypertension, being overweight, and any other pathology linked to metabolic syndrome, which is so prevalent today, through health programs beginning at a young age.
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spelling pubmed-101776212023-05-13 Influence of Adipose Tissue on Early Metabolic Programming: Conditioning Factors and Early Screening Puche-Juarez, Maria Toledano, Juan M. Ochoa, Julio J. Diaz-Castro, Javier Moreno-Fernandez, Jorge Diagnostics (Basel) Review Background: Obesity and being overweight have become one of the world’s most severe health issues, not only because of the pathology but also because of the development of related comorbidities. Even when children reach adulthood, the mother’s environment during pregnancy has been found to have a significant impact on obesity prevention in children. Thus, both maternal dietary habits and other factors such as gestational diabetes mellitus, excessive weight gain during pregnancy, smoking, or endocrine factors, among others, could influence newborn growth, adiposity, and body composition at birth, in childhood and adolescence, hence programming health in adulthood. Methods: The aim of this review is to analyze the most recent human studies on the programming of fetal adipose tissue to determine which modifiable factors may influence adiposity and thus prevent specific disorders later in life by means of a bibliographic review of articles related to the subject over the last ten years. Conclusions: The importance of a healthy diet and lifestyle not only during pregnancy and the first months of life but also throughout childhood, especially during the first two years of life as this is a period of great plasticity, where the foundations for optimal health in later life will be laid, preventing the emergence of noncommunicable diseases including obesity, diabetes mellitus type 2, hypertension, being overweight, and any other pathology linked to metabolic syndrome, which is so prevalent today, through health programs beginning at a young age. MDPI 2023-04-22 /pmc/articles/PMC10177621/ /pubmed/37174902 http://dx.doi.org/10.3390/diagnostics13091510 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Puche-Juarez, Maria
Toledano, Juan M.
Ochoa, Julio J.
Diaz-Castro, Javier
Moreno-Fernandez, Jorge
Influence of Adipose Tissue on Early Metabolic Programming: Conditioning Factors and Early Screening
title Influence of Adipose Tissue on Early Metabolic Programming: Conditioning Factors and Early Screening
title_full Influence of Adipose Tissue on Early Metabolic Programming: Conditioning Factors and Early Screening
title_fullStr Influence of Adipose Tissue on Early Metabolic Programming: Conditioning Factors and Early Screening
title_full_unstemmed Influence of Adipose Tissue on Early Metabolic Programming: Conditioning Factors and Early Screening
title_short Influence of Adipose Tissue on Early Metabolic Programming: Conditioning Factors and Early Screening
title_sort influence of adipose tissue on early metabolic programming: conditioning factors and early screening
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177621/
https://www.ncbi.nlm.nih.gov/pubmed/37174902
http://dx.doi.org/10.3390/diagnostics13091510
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