Cargando…

Nutri-PEITC Jelly Significantly Improves Progression-Free Survival and Quality of Life in Patients with Advanced Oral and Oropharyngeal Cancer: A Blinded Randomized Placebo-Controlled Trial

TP53 mutation is associated with cancer progression. Novel strategies to reboot p53 are required to stabilize the disease and improve survival. This randomized placebo-controlled trial investigated safety and efficacy of Nutri-PEITC Jelly (a texture-modified nutritious diet fortified with β-phenethy...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lam-Ubol, Aroonwan, Sukhaboon, Jirasak, Rasio, Withee, Tupwongse, Peerawitch, Tangshewinsirikul, Thapana, Trachootham, Dunyaporn
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177844/ https://www.ncbi.nlm.nih.gov/pubmed/37175527 http://dx.doi.org/10.3390/ijms24097824

Ejemplares similares

Nutri-jelly may improve quality of life and decrease tube feeding demand in head and neck cancer patients
por: Trachootham, Dunyaporn, et al.
Publicado: (2014)

Simultaneously complete but not partial taste and smell losses were associated with SARS-CoV-2 infection
por: Trachootham, Dunyaporn, et al.
Publicado: (2021)

Partial Substitution of Glucose with Xylitol Prolongs Survival and Suppresses Cell Proliferation and Glycolysis of Mice Bearing Orthotopic Xenograft of Oral Cancer
por: Sahasakul, Yuraporn, et al.
Publicado: (2022)

Alleviation of dry mouth by saliva substitutes improved swallowing ability and clinical nutritional status of post-radiotherapy head and neck cancer patients: a randomized controlled trial
por: Nuchit, Sumalee, et al.
Publicado: (2019)

Efficacy of gel-based artificial saliva on Candida colonization and saliva properties in xerostomic post-radiotherapy head and neck cancer patients: a randomized controlled trial
por: Lam-ubol, Aroonwan, et al.
Publicado: (2020)

Distinct histone H3 modification profiles correlate with aggressive characteristics of salivary gland neoplasms
por: Lam-Ubol, Aroonwan, et al.
Publicado: (2022)

Disrupting redox stabilizer: a novel therapeutic strategy for colorectal cancer
por: Trachootham, Dunyaporn, et al.
Publicado: (2019)

An Individuality of Response to Cannabinoids: Challenges in Safety and Efficacy of Cannabis Products
por: Kitdumrongthum, Sarunya, et al.
Publicado: (2023)

A Green Extraction Method to Achieve the Highest Yield of Limonin and Hesperidin from Lime Peel Powder (Citrus aurantifolia)
por: Phucharoenrak, Pakkapong, et al.
Publicado: (2022)

Twelve-Week Safety and Potential Lipid Control Efficacy of Coffee Cherry Pulp Juice Concentrate in Healthy Volunteers
por: Rungraung, Numphung, et al.
Publicado: (2023)

Metabolomic Analysis of Phytochemical Compounds from Ethanolic Extract of Lime (Citrus aurantifolia) Peel and Its Anti-Cancer Effects against Human Hepatocellular Carcinoma Cells
por: Phucharoenrak, Pakkapong, et al.
Publicado: (2023)

Glandular odontogenic cyst of the mandible: A case report
por: Udompatanakorn, Chatchaphan, et al.
Publicado: (2023)

Central Odontogenic Myxoma: A Radiographic Analysis
por: Ghazali, Ahmad Badruddin, et al.
Publicado: (2021)

Cooking Methods for Preserving Isothiocyanates and Reducing Goitrin in Brassica Vegetables
por: Panduang, Thanaporn, et al.
Publicado: (2023)

Synergistic Microbicidal Effect of AUR and PEITC Against Staphylococcus aureus Skin Infection
por: Chen, Haoran, et al.
Publicado: (2022)

Toll-like receptor 2 induces adenosine receptor A2a and promotes human squamous carcinoma cell growth via extracellular signal regulated kinases ½
por: Palani, Chithra Devi, et al.
Publicado: (2017)

Oral manifestations, salivary flow rates and Candida species in Thai HIV-infected patients
por: Lam-ubol, Aroonwan, et al.
Publicado: (2019)

Loss of Eicosapentaenoic Acid (EPA) after Retort Sterilization of the EPA-BCAA Fortified Complete Nutrition Drink
por: Khoonin, Watcharapol, et al.
Publicado: (2022)

Dietary phytochemical PEITC restricts tumor development via modulation of epigenetic writers and erasers
por: Park, Jung Eun, et al.
Publicado: (2017)

Complete nutrition drink with retrograded starch is low glycemic, and the individual glucose response to the low glycemic complete nutrition drink depends on fasting insulin levels and HOMA-IR in a randomized cross-over control trial
por: Wongniyomkaset, Warisara, et al.
Publicado: (2022)

ROS Accumulation by PEITC Selectively Kills Ovarian Cancer Cells via UPR-Mediated Apoptosis
por: Hong, Yoon-Hee, et al.
Publicado: (2015)

Irreversible Inhibition of Glutathione S-Transferase by Phenethyl Isothiocyanate (PEITC), a Dietary Cancer Chemopreventive Phytochemical
por: Kumari, Vandana, et al.
Publicado: (2016)

Direct Inhibition of GSDMD by PEITC Reduces Hepatocyte Pyroptosis and Alleviates Acute Liver Injury in Mice
por: Wang, Jie, et al.
Publicado: (2022)

Eicosapentaenoic acid and branched-chain amino acids fortified complete nutrition drink improved muscle strength in older individuals with inadequate protein intake
por: Khoonin, Watcharapol, et al.
Publicado: (2023)

Cisplatin in combination with Phenethyl Isothiocyanate (PEITC), a potential new therapeutic strategy for malignant pleural mesothelioma
por: Denis, Iza, et al.
Publicado: (2014)

Nutri-Calc HD
por: Mayne, Susan Taylor
Publicado: (1990)

Metabolic targets of watercress and PEITC in MCF-7 and MCF-10A cells explain differential sensitisation responses to ionising radiation
por: Giallourou, Natasa S., et al.
Publicado: (2018)

BAG3 down-modulation sensitizes HPV18(+) HeLa cells to PEITC-induced apoptosis and restores p53
por: Cotugno, Roberta, et al.
Publicado: (2014)

PEITC: A resounding molecule averts metastasis in breast cancer cells in vitro by regulating PKCδ/Aurora A interplay
por: Biswas, Souvick, et al.
Publicado: (2022)

Nutritional Assessment of Ready-to-Eat Salads in German Supermarkets: Comparison of the nutriRECIPE-Index and the Nutri-Score
por: Schlarbaum, Laura, et al.
Publicado: (2022)

PEITC triggers multiple forms of cell death by GSH-iron-ROS regulation in K7M2 murine osteosarcoma cells
por: Lv, Huan-huan, et al.
Publicado: (2020)

Royal Jelly Increases Hematopoietic Stem Cells in Peripheral Blood: A Double-Blind, Placebo-Controlled, Randomized Trial in Healthy Subjects
por: Okamoto, Hideto, et al.
Publicado: (2023)

Effects of Methylsulfonylmethane (MSM) on exercise-induced oxidative stress, muscle damage, and pain following a half-marathon: a double-blind, randomized, placebo-controlled trial
por: Withee, Eric D., et al.
Publicado: (2017)

Diplazium esculentum (Retz.) Sw. reduces BACE-1 activities and amyloid peptides accumulation in Drosophila models of Alzheimer’s disease
por: Kunkeaw, Thanit, et al.
Publicado: (2021)

Effects of probiotic supplements on insulin resistance in gestational diabetes mellitus: A double‐blind randomized controlled trial
por: Kijmanawat, Athasit, et al.
Publicado: (2018)

Metabolic syndrome: Nutri-epigenetic cause or consequence?
por: Silva-Ochoa, Alfonso D., et al.
Publicado: (2023)

Clinical Evaluation of a Royal Jelly Supplementation for the Restoration of Dry Eye: A Prospective Randomized Double Blind Placebo Controlled Study and an Experimental Mouse Model
por: Inoue, Sachiko, et al.
Publicado: (2017)

Effects of protease-treated royal jelly on muscle strength in elderly nursing home residents: A randomized, double-blind, placebo-controlled, dose-response study
por: Meng, Ge, et al.
Publicado: (2017)

Two Dimensions of Nutritional Value: Nutri-Score and NOVA
por: Romero Ferreiro, Carmen, et al.
Publicado: (2021)

Evaluation of Psychometric Properties of NutriCHEQ in Iranian Toddlers
por: Tajalli, Saleheh, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_bk41p9iohvghfbmathhavrojrk