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Exercise and Doxorubicin Modify Markers of Iron Overload and Cardiolipin Deficiency in Cardiac Mitochondria
Doxorubicin (DOX) is a chemotherapeutic agent highly effective at limiting cancer progression. Despite the efficacy of this anticancer drug, the clinical use of DOX is limited due to cardiotoxicity. The cardiac mitochondria are implicated as the primary target of DOX, resulting in inactivation of el...
Autores principales: | Montalvo, Ryan N., Boeno, Franccesco P., Dowllah, Imtiaz M., Moritz, Cesar E. Jacintho, Nguyen, Branden L., Doerr, Vivian, Bomkamp, Matthew P., Smuder, Ashley J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177936/ https://www.ncbi.nlm.nih.gov/pubmed/37175395 http://dx.doi.org/10.3390/ijms24097689 |
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