Novel quinoline/thiazinan-4-one hybrids; design, synthesis, and molecular docking studies as potential anti-bacterial candidates against MRSA

In an attempt to develop effective and safe antibacterial agents, we synthesized novel thiazinanones by combining the quinolone scaffold and the 1,3-thiazinan-4-one group by reaction between ((4-hydroxy-2-oxo-1,2-dihydroquinolin-3-yl)methylene)hydrazinecarbothioamides and 2,3-diphenylcycloprop-2-eno...

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Detalles Bibliográficos
Autores principales: Mohamed, Asmaa H., Mostafa, Sara M., Aly, Ashraf A., Hassan, Alaa A., Osman, Esraa M., Nayl, AbdElAziz A., Brown, Alan B., Abdelhafez, Elshimaa M. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178015/
https://www.ncbi.nlm.nih.gov/pubmed/37188251
http://dx.doi.org/10.1039/d3ra01721d

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178015/
https://www.ncbi.nlm.nih.gov/pubmed/37188251
http://dx.doi.org/10.1039/d3ra01721d

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