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The E3 Ubiquitin Ligase TRIM21 Regulates Basal Levels of PDGFRβ
Activation of platelet-derived growth factor (PDGF) receptors α and β (PDGFRα and PDGFRβ) at the cell surface by binding of PDGF isoforms leads to internalization of receptors, which affects the amplitude and kinetics of signaling. Ubiquitination of PDGF receptors in response to ligand stimulation i...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178120/ https://www.ncbi.nlm.nih.gov/pubmed/37175489 http://dx.doi.org/10.3390/ijms24097782 |