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Meniscal Allograft Transplants in Skeletally Immature Patients: A Systematic Review of Indications and Outcomes

Meniscal lesions in skeletally immature patients can lead to joint degradation and knee instability. Meniscal allograft transplant (MAT) surgery is a solution to maintain knee stability. There is a lack of consensus on MAT surgery outcomes in pediatric patients. A systematic review was conducted acc...

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Autores principales: Turati, Marco, Boerci, Linda, Piatti, Massimiliano, Russo, Laura, Rigamonti, Luca, Buonanotte, Francesco, Courvoisier, Aurelien, Zatti, Giovanni, Piscitelli, Daniele, Bigoni, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178226/
https://www.ncbi.nlm.nih.gov/pubmed/37174854
http://dx.doi.org/10.3390/healthcare11091312
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author Turati, Marco
Boerci, Linda
Piatti, Massimiliano
Russo, Laura
Rigamonti, Luca
Buonanotte, Francesco
Courvoisier, Aurelien
Zatti, Giovanni
Piscitelli, Daniele
Bigoni, Marco
author_facet Turati, Marco
Boerci, Linda
Piatti, Massimiliano
Russo, Laura
Rigamonti, Luca
Buonanotte, Francesco
Courvoisier, Aurelien
Zatti, Giovanni
Piscitelli, Daniele
Bigoni, Marco
author_sort Turati, Marco
collection PubMed
description Meniscal lesions in skeletally immature patients can lead to joint degradation and knee instability. Meniscal allograft transplant (MAT) surgery is a solution to maintain knee stability. There is a lack of consensus on MAT surgery outcomes in pediatric patients. A systematic review was conducted according to the PRISMA guidelines. PubMed, Scopus and EMBASE databases were searched from 1965 to June 2022. Studies were evaluated using the Newcastle–Ottawa Scale (NOS). Three studies were selected, and 58 patients were included (mean age 15.9 years) in total. The lateral meniscus was involved in 82.8% of all MAT surgeries. Post-meniscectomy syndrome and discoid meniscus were the main indications for MAT surgery. All studies reported improved subjective clinical scores and levels of sport after the surgery. The complication rate was 27.5%. Partial meniscectomy, meniscus knot removal, chondral defect treatment and lysis of adhesions were the most frequent procedures performed during reoperation. MAT surgery can improve clinical outcomes in pediatric patients with strictly selected indications. MAT surgery is safe when there are no limb asymmetries or malalignments, but it remains a challenging procedure with a high complication rate. Long-term follow-up is needed for definitive statements on the use of MAT in skeletally immature patients.
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spelling pubmed-101782262023-05-13 Meniscal Allograft Transplants in Skeletally Immature Patients: A Systematic Review of Indications and Outcomes Turati, Marco Boerci, Linda Piatti, Massimiliano Russo, Laura Rigamonti, Luca Buonanotte, Francesco Courvoisier, Aurelien Zatti, Giovanni Piscitelli, Daniele Bigoni, Marco Healthcare (Basel) Review Meniscal lesions in skeletally immature patients can lead to joint degradation and knee instability. Meniscal allograft transplant (MAT) surgery is a solution to maintain knee stability. There is a lack of consensus on MAT surgery outcomes in pediatric patients. A systematic review was conducted according to the PRISMA guidelines. PubMed, Scopus and EMBASE databases were searched from 1965 to June 2022. Studies were evaluated using the Newcastle–Ottawa Scale (NOS). Three studies were selected, and 58 patients were included (mean age 15.9 years) in total. The lateral meniscus was involved in 82.8% of all MAT surgeries. Post-meniscectomy syndrome and discoid meniscus were the main indications for MAT surgery. All studies reported improved subjective clinical scores and levels of sport after the surgery. The complication rate was 27.5%. Partial meniscectomy, meniscus knot removal, chondral defect treatment and lysis of adhesions were the most frequent procedures performed during reoperation. MAT surgery can improve clinical outcomes in pediatric patients with strictly selected indications. MAT surgery is safe when there are no limb asymmetries or malalignments, but it remains a challenging procedure with a high complication rate. Long-term follow-up is needed for definitive statements on the use of MAT in skeletally immature patients. MDPI 2023-05-03 /pmc/articles/PMC10178226/ /pubmed/37174854 http://dx.doi.org/10.3390/healthcare11091312 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Turati, Marco
Boerci, Linda
Piatti, Massimiliano
Russo, Laura
Rigamonti, Luca
Buonanotte, Francesco
Courvoisier, Aurelien
Zatti, Giovanni
Piscitelli, Daniele
Bigoni, Marco
Meniscal Allograft Transplants in Skeletally Immature Patients: A Systematic Review of Indications and Outcomes
title Meniscal Allograft Transplants in Skeletally Immature Patients: A Systematic Review of Indications and Outcomes
title_full Meniscal Allograft Transplants in Skeletally Immature Patients: A Systematic Review of Indications and Outcomes
title_fullStr Meniscal Allograft Transplants in Skeletally Immature Patients: A Systematic Review of Indications and Outcomes
title_full_unstemmed Meniscal Allograft Transplants in Skeletally Immature Patients: A Systematic Review of Indications and Outcomes
title_short Meniscal Allograft Transplants in Skeletally Immature Patients: A Systematic Review of Indications and Outcomes
title_sort meniscal allograft transplants in skeletally immature patients: a systematic review of indications and outcomes
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178226/
https://www.ncbi.nlm.nih.gov/pubmed/37174854
http://dx.doi.org/10.3390/healthcare11091312
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