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Identification of Piperlongumine as Potent Inhibitor of Necroptosis

PURPOSE: Excessive necroptosis contributes to the pathogenesis of several inflammatory and neurodegenerative diseases. Here, using a high-throughput screening approach, we investigated the anti-necroptosis effects of piperlongumine, an alkaloid isolated from the long pepper plant, in vitro and in a...

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Detalles Bibliográficos
Autores principales:	He, Xiaoyan, Li, Min, Ye, Zhi, You, Xiaoling, Wang, Jia, Xiao, Xin, Zhu, Guofeng, Wei, Jun, Zha, Yunhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2023
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178306/ https://www.ncbi.nlm.nih.gov/pubmed/37188283 http://dx.doi.org/10.2147/DDDT.S397971

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