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Identification of Piperlongumine as Potent Inhibitor of Necroptosis
PURPOSE: Excessive necroptosis contributes to the pathogenesis of several inflammatory and neurodegenerative diseases. Here, using a high-throughput screening approach, we investigated the anti-necroptosis effects of piperlongumine, an alkaloid isolated from the long pepper plant, in vitro and in a...
Autores principales: | He, Xiaoyan, Li, Min, Ye, Zhi, You, Xiaoling, Wang, Jia, Xiao, Xin, Zhu, Guofeng, Wei, Jun, Zha, Yunhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178306/ https://www.ncbi.nlm.nih.gov/pubmed/37188283 http://dx.doi.org/10.2147/DDDT.S397971 |
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