Cargando…
Telmisartan Is a Promising Agent for Managing Neuropathic Pain and Delaying Opioid Analgesic Tolerance in Rats
Despite the large arsenal of analgesic medications, neuropathic pain (NP) management is not solved yet. Angiotensin II receptor type 1 (AT1) has been identified as a potential target in NP therapy. Here, we investigate the antiallodynic effect of AT1 blockers telmisartan and losartan, and particular...
Autores principales: | Karádi, David Á., Galambos, Anna Rita, Lakatos, Péter P., Apenberg, Joost, Abbood, Sarah K., Balogh, Mihály, Király, Kornél, Riba, Pál, Essmat, Nariman, Szűcs, Edina, Benyhe, Sándor, Varga, Zoltán V., Szökő, Éva, Tábi, Tamás, Al-Khrasani, Mahmoud |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178315/ https://www.ncbi.nlm.nih.gov/pubmed/37175678 http://dx.doi.org/10.3390/ijms24097970 |
Ejemplares similares
-
Pregabalin–Tolperisone Combination to Treat Neuropathic Pain: Improved Analgesia and Reduced Side Effects in Rats
por: Essmat, Nariman, et al.
Publicado: (2023) -
The Acute Antiallodynic Effect of Tolperisone in Rat Neuropathic Pain and Evaluation of Its Mechanism of Action
por: Lakatos, Péter P., et al.
Publicado: (2022) -
Pharmacological Evidence on Augmented Antiallodynia Following Systemic Co-Treatment with GlyT-1 and GlyT-2 Inhibitors in Rat Neuropathic Pain Model
por: Mohammadzadeh, Amir, et al.
Publicado: (2021) -
Shedding Light on the Pharmacological Interactions between μ-Opioid Analgesics and Angiotensin Receptor Modulators: A New Option for Treating Chronic Pain
por: Király, Kornél, et al.
Publicado: (2021) -
Recent Molecular Insights into Agonist-specific Binding to the Mu-Opioid Receptor
por: Zádor, Ferenc, et al.
Publicado: (2022)