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Immortalization Reversibility in the Context of Cell Therapy Biosafety

Immortalization (genetically induced prevention of replicative senescence) is a promising approach to obtain cellular material for cell therapy or for bio-artificial organs aimed at overcoming the problem of donor material shortage. Immortalization is reversed before cells are used in vivo to allow...

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Detalles Bibliográficos
Autores principales: Sutyagina, Oksana I., Beilin, Arkadii K., Vorotelyak, Ekaterina A., Vasiliev, Andrey V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178325/
https://www.ncbi.nlm.nih.gov/pubmed/37175444
http://dx.doi.org/10.3390/ijms24097738