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Optogenetic Globus Pallidus Stimulation Improves Motor Deficits in 6-Hydroxydopamine-Lesioned Mouse Model of Parkinson’s Disease

Excessive inhibition of the external globus pallidus (GPe) by striatal GABAergic neurons is considered a central mechanism contributing to motor symptoms of Parkinson’s disease (PD). While electrophysiological findings support this view, behavioral studies assessing the beneficial effects of global...

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Detalles Bibliográficos
Autores principales: Di Bisceglie Caballero, Sonia, Ces, Aurelia, Liberge, Martine, Ambroggi, Frederic, Amalric, Marianne, Ouagazzal, Abdel-Mouttalib
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178372/
https://www.ncbi.nlm.nih.gov/pubmed/37175643
http://dx.doi.org/10.3390/ijms24097935

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