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A Promising Way to Overcome Temozolomide Resistance through Inhibition of Protein Neddylation in Glioblastoma Cell Lines
There is no effective therapy for the lately increased incidence of glioblastoma multiforme (GBM)—the most common primary brain tumor characterized by a high degree of invasiveness and genetic heterogeneity. Currently, DNA alkylating agent temozolomide (TMZ) is the standard chemotherapy. Nevertheles...
Autores principales: | Brandt, Barbara, Németh, Marica, Berta, Gergely, Szünstein, Máté, Heffer, Marija, Rauch, Tibor A., Pap, Marianna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178391/ https://www.ncbi.nlm.nih.gov/pubmed/37175636 http://dx.doi.org/10.3390/ijms24097929 |
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