Development and implementation of an automated and highly accurate reporting process for NGS-based clonality testing

B and T cells undergo random recombination of the VH/DH/JH portions of the immunoglobulin loci (B cell) and T-cell receptors before becoming functional cells. When one V-J rearrangement is over-represented in a population of B or T cells indicating an origin from a single cell, this indicates a clon...

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Detalles Bibliográficos
Autores principales: Glenn, Sean T., Galbo, Phillip M., Luce, Jesse D., Miles, Kiersten Marie, Singh, Prashant K., Glynias, Manuel J., Morrison, Carl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178459/
https://www.ncbi.nlm.nih.gov/pubmed/37171376
http://dx.doi.org/10.18632/oncotarget.28429

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178459/
https://www.ncbi.nlm.nih.gov/pubmed/37171376
http://dx.doi.org/10.18632/oncotarget.28429

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