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A Histogram Analysis of the Pixel Grayscale (Luminous Intensity) of B-Mode Ultrasound Images of the Subcutaneous Layer Predicts the Grade of Leg Edema in Pregnant Women

The technique most widely used to quantitatively measure leg edema is only a pitting edema method. It has recently become possible to digitize B-mode ultrasound images and accurately quantify their brightness using an image-analysis software program. The purpose of this study was to find new indices...

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Autores principales: Ikuta, Eri, Koshiyama, Masafumi, Watanabe, Yumiko, Banba, Airi, Yanagisawa, Nami, Nakagawa, Miwa, Ono, Ayumi, Seki, Keiko, Kambe, Haruki, Godo, Taiki, Sakamoto, Shin-ichi, Hara, Yoko, Nakajima, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178771/
https://www.ncbi.nlm.nih.gov/pubmed/37174870
http://dx.doi.org/10.3390/healthcare11091328
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author Ikuta, Eri
Koshiyama, Masafumi
Watanabe, Yumiko
Banba, Airi
Yanagisawa, Nami
Nakagawa, Miwa
Ono, Ayumi
Seki, Keiko
Kambe, Haruki
Godo, Taiki
Sakamoto, Shin-ichi
Hara, Yoko
Nakajima, Akira
author_facet Ikuta, Eri
Koshiyama, Masafumi
Watanabe, Yumiko
Banba, Airi
Yanagisawa, Nami
Nakagawa, Miwa
Ono, Ayumi
Seki, Keiko
Kambe, Haruki
Godo, Taiki
Sakamoto, Shin-ichi
Hara, Yoko
Nakajima, Akira
author_sort Ikuta, Eri
collection PubMed
description The technique most widely used to quantitatively measure leg edema is only a pitting edema method. It has recently become possible to digitize B-mode ultrasound images and accurately quantify their brightness using an image-analysis software program. The purpose of this study was to find new indices of the grade of leg skin, to study whether or not analyses of the subcutaneous layer of leg skin on ultrasound images using image-editing software program can be used to evaluate it and to digitize it. Images of 282 subcutaneous layers of leg skin in 141 pregnant women were obtained using a B-scan portable ultrasound device. Rectangular photographs (vertical: skin thickness; horizontal: width of probe) were obtained using an image-editing program, and the luminous intensity (pixel grayscale: 0–255) and thickness of the skin were calculated using a histogram. We investigated the correlation between these parameters and the grade of pitting edema (0–3). There was a significant positive correlation between the grade of pitting edema and the average luminous intensity value, its standard deviation, and the skin thickness (ρ = 0.36, ρ = 0.22, ρ = 0.51, p < 0.0001, respectively). In particular, there was strong positive correlation between the grade of pitting edema and both the total number of pixels in a rectangle × (multiplied by) the average luminous intensity value and the total number of pixels in a rectangle × the standard deviation of the average luminous intensity value (ρ = 0.58 and ρ = 0.59, p < 0.0001, respectively). We could quantitatively evaluate the grade of leg edema by analyzing ultrasound photographs of the subcutaneous layer of the leg skin using an image-editing software program and found new indices to digitize it.
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spelling pubmed-101787712023-05-13 A Histogram Analysis of the Pixel Grayscale (Luminous Intensity) of B-Mode Ultrasound Images of the Subcutaneous Layer Predicts the Grade of Leg Edema in Pregnant Women Ikuta, Eri Koshiyama, Masafumi Watanabe, Yumiko Banba, Airi Yanagisawa, Nami Nakagawa, Miwa Ono, Ayumi Seki, Keiko Kambe, Haruki Godo, Taiki Sakamoto, Shin-ichi Hara, Yoko Nakajima, Akira Healthcare (Basel) Brief Report The technique most widely used to quantitatively measure leg edema is only a pitting edema method. It has recently become possible to digitize B-mode ultrasound images and accurately quantify their brightness using an image-analysis software program. The purpose of this study was to find new indices of the grade of leg skin, to study whether or not analyses of the subcutaneous layer of leg skin on ultrasound images using image-editing software program can be used to evaluate it and to digitize it. Images of 282 subcutaneous layers of leg skin in 141 pregnant women were obtained using a B-scan portable ultrasound device. Rectangular photographs (vertical: skin thickness; horizontal: width of probe) were obtained using an image-editing program, and the luminous intensity (pixel grayscale: 0–255) and thickness of the skin were calculated using a histogram. We investigated the correlation between these parameters and the grade of pitting edema (0–3). There was a significant positive correlation between the grade of pitting edema and the average luminous intensity value, its standard deviation, and the skin thickness (ρ = 0.36, ρ = 0.22, ρ = 0.51, p < 0.0001, respectively). In particular, there was strong positive correlation between the grade of pitting edema and both the total number of pixels in a rectangle × (multiplied by) the average luminous intensity value and the total number of pixels in a rectangle × the standard deviation of the average luminous intensity value (ρ = 0.58 and ρ = 0.59, p < 0.0001, respectively). We could quantitatively evaluate the grade of leg edema by analyzing ultrasound photographs of the subcutaneous layer of the leg skin using an image-editing software program and found new indices to digitize it. MDPI 2023-05-05 /pmc/articles/PMC10178771/ /pubmed/37174870 http://dx.doi.org/10.3390/healthcare11091328 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Brief Report
Ikuta, Eri
Koshiyama, Masafumi
Watanabe, Yumiko
Banba, Airi
Yanagisawa, Nami
Nakagawa, Miwa
Ono, Ayumi
Seki, Keiko
Kambe, Haruki
Godo, Taiki
Sakamoto, Shin-ichi
Hara, Yoko
Nakajima, Akira
A Histogram Analysis of the Pixel Grayscale (Luminous Intensity) of B-Mode Ultrasound Images of the Subcutaneous Layer Predicts the Grade of Leg Edema in Pregnant Women
title A Histogram Analysis of the Pixel Grayscale (Luminous Intensity) of B-Mode Ultrasound Images of the Subcutaneous Layer Predicts the Grade of Leg Edema in Pregnant Women
title_full A Histogram Analysis of the Pixel Grayscale (Luminous Intensity) of B-Mode Ultrasound Images of the Subcutaneous Layer Predicts the Grade of Leg Edema in Pregnant Women
title_fullStr A Histogram Analysis of the Pixel Grayscale (Luminous Intensity) of B-Mode Ultrasound Images of the Subcutaneous Layer Predicts the Grade of Leg Edema in Pregnant Women
title_full_unstemmed A Histogram Analysis of the Pixel Grayscale (Luminous Intensity) of B-Mode Ultrasound Images of the Subcutaneous Layer Predicts the Grade of Leg Edema in Pregnant Women
title_short A Histogram Analysis of the Pixel Grayscale (Luminous Intensity) of B-Mode Ultrasound Images of the Subcutaneous Layer Predicts the Grade of Leg Edema in Pregnant Women
title_sort histogram analysis of the pixel grayscale (luminous intensity) of b-mode ultrasound images of the subcutaneous layer predicts the grade of leg edema in pregnant women
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178771/
https://www.ncbi.nlm.nih.gov/pubmed/37174870
http://dx.doi.org/10.3390/healthcare11091328
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