Modulating fast skeletal muscle contraction protects skeletal muscle in animal models of Duchenne muscular dystrophy

Duchenne muscular dystrophy (DMD) is a lethal muscle disease caused by absence of the protein dystrophin, which acts as a structural link between the basal lamina and contractile machinery to stabilize muscle membranes in response to mechanical stress. In DMD, mechanical stress leads to exaggerated...

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Detalles Bibliográficos
Autores principales: Russell, Alan J., DuVall, Mike, Barthel, Ben, Qian, Ying, Peter, Angela K., Newell-Stamper, Breanne L., Hunt, Kevin, Lehman, Sarah, Madden, Molly, Schlachter, Stephen, Robertson, Ben, Van Deusen, Ashleigh, Rodriguez, Hector M., Vera, Carlos, Su, Yu, Claflin, Dennis R., Brooks, Susan V., Nghiem, Peter, Rutledge, Alexis, Juehne, Twlya I., Yu, Jinsheng, Barton, Elisabeth R., Luo, Yangyi E., Patsalos, Andreas, Nagy, Laszlo, Sweeney, H. Lee, Leinwand, Leslie A., Koch, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178848/
https://www.ncbi.nlm.nih.gov/pubmed/36995778
http://dx.doi.org/10.1172/JCI153837

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