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PD-L1 Exon 3 Is a Hidden Switch of Its Expression and Function in Oral Cancer Cells

The interaction between programmed cell death 1 ligand 1 (PD-L1) and programmed cell death protein 1 (PD-1) protects tumor cells from immune surveillance. PD-L1 exon 3 is a potential alternative exon and encodes an Ig variable (IgV) domain. Here, we found that a lack of exon 3 leads to the significa...

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Detalles Bibliográficos
Autores principales: Yan, Lingyan, Sun, Yanan, Guo, Jihua, Jia, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178889/
https://www.ncbi.nlm.nih.gov/pubmed/37175900
http://dx.doi.org/10.3390/ijms24098193