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The Antiangiogenic Effect and Ocular Pharmacology of Novel Modified Nonsteroidal Anti-Inflammatory Drugs in the Treatment of Oxygen-Induced Retinopathy

PURPOSE: To evaluate the hypothesis that 3 novel compounds, OXT-328, Q-922, and CL-717 show efficacy in the treatment of oxygen-induced retinopathy (OIR) and whether or not their route of administration is intravitreal, topical, or systemic. METHODS: The OIR mouse model, characterized by an avascula...

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Detalles Bibliográficos
Autores principales: Huang, Wei, Huang, Liqun, Wen, Ziyi, Honkanen, Robert A., Rigas, Basil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178932/
https://www.ncbi.nlm.nih.gov/pubmed/37172294
http://dx.doi.org/10.1089/jop.2022.0113

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