Cargando…

Analysis of Circulating Tumor DNA in Synchronous Metastatic Colorectal Cancer at Diagnosis Predicts Overall Patient Survival

Sporadic colorectal cancer (sCRC) initially presents as metastatic tumors in 25–30% of patients. The 5-year overall survival (OS) in patients with metastatic sCRC is 50%, falling to 10% in patients presenting with synchronous metastatic disease (stage IV). In this study, we systematically analyzed t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sayagués, José María, Montero, Juan Carlos, Jiménez-Pérez, Andrea, del Carmen, Sofía, Rodríguez, Marta, Vidal Tocino, Rosario, Montero, Enrique, Sanz, Julia, Abad, Mar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179090/ https://www.ncbi.nlm.nih.gov/pubmed/37176143 http://dx.doi.org/10.3390/ijms24098438

Ejemplares similares

Dysregulated Expression of Three Genes in Colorectal Cancer Stratifies Patients into Three Risk Groups
por: Rodriguez, Alba, et al.
Publicado: (2022)

An amino acid transporter subunit as an antibody–drug conjugate target in colorectal cancer
por: Montero, Juan Carlos, et al.
Publicado: (2023)

High-Risk Clinicopathological and Genetic Features and Outcomes in Patients Receiving Neoadjuvant Radiochemotherapy for Locally Advanced Rectal Cancer
por: del Carmen, Sofía, et al.
Publicado: (2021)

Does primary tumor resection contribute to overall survival in unresectable synchronous metastatic colorectal cancer?
por: Ergun, Yakup, et al.
Publicado: (2020)

Circulating inflammation signature predicts overall survival and relapse-free survival in metastatic colorectal cancer
por: Varkaris, Andreas, et al.
Publicado: (2019)

Prognostic impact of a novel gene expression profile classifier for the discrimination between metastatic and non-metastatic primary colorectal cancer tumors
por: Gutiérrez, María Laura, et al.
Publicado: (2017)

Surfaceome analyses uncover CD98hc as an antibody drug-conjugate target in triple negative breast cancer
por: Montero, Juan Carlos, et al.
Publicado: (2022)

Drug Holidays and Overall Survival of Patients with Metastatic Colorectal Cancer
por: Garattini, Silvio Ken, et al.
Publicado: (2021)

The Impact of Liquid Biopsies Positive for EGFR Mutations on Overall Survival in Non-Small Cell Lung Cancer Patients
por: Roldan Ruiz, Jonnathan, et al.
Publicado: (2023)

Spatio-temporal tumor heterogeneity in metastatic CRC tumors: a mutational-based approach
por: del Carmen, Sofía, et al.
Publicado: (2018)

Nomograms predicting Overall Survival and Cancer-specific Survival for Synchronous Colorectal Liver-limited Metastasis
por: Li, Yuqiang, et al.
Publicado: (2020)

Metastatic colorectal cancer-prolonging overall survival with targeted therapies
por: Dattatreya, Satya
Publicado: (2013)

Prognostic implications of EGFR protein expression in sporadic colorectal tumors: Correlation with copy number status, mRNA levels and miRNA regulation
por: del Carmen, Sofía, et al.
Publicado: (2020)

The Impact of Primary Tumor Location in Synchronous Metastatic Colorectal Cancer: Differences in Metastatic Sites and Survival
por: Brouwer, Nelleke P. M., et al.
Publicado: (2019)

Genomic characterization of liver metastases from colorectal cancer patients
por: Sayagués, José María, et al.
Publicado: (2016)

Assessment of Overall Survival Benefits in Patients Undergoing Complete Hepatectomy for Synchronous Colorectal Cancer With Liver and Lung Metastases
por: Arvide, Elsa Melissa, et al.
Publicado: (2016)

Classification of patients with metastatic colorectal cancer into consensus molecular subtypes into real-world: A pilot study
por: González-Montero, Jaime, et al.
Publicado: (2023)

Sex differences in metastatic surgery following diagnosis of synchronous metastatic colorectal cancer
por: Ljunggren, Malin, et al.
Publicado: (2022)

Progression-free survival as a surrogate endpoint of overall survival in patients with metastatic colorectal cancer
por: Cicero, Giuseppe, et al.
Publicado: (2018)

Hypertension and overall survival in metastatic colorectal cancer patients treated with bevacizumab-containing chemotherapy
por: Österlund, P, et al.
Publicado: (2011)

Metabolic Parameters as Predictors for Progression Free and Overall Survival of Patients with Metastatic Colorectal Cancer
por: Nemeth, Zsuzsanna, et al.
Publicado: (2020)

Physical Activity Is Associated with Improved Overall Survival among Patients with Metastatic Colorectal Cancer
por: Smit, Karel C., et al.
Publicado: (2022)

Comparative Genomic Analysis of Primary and Synchronous Metastatic Colorectal Cancers
por: Lee, Sun Young, et al.
Publicado: (2014)

The immune cell landscape of metastatic uveal melanoma correlates with overall survival
por: Tosi, Anna, et al.
Publicado: (2021)

Combined assessment of the TNM stage and BRAF mutational status at diagnosis in sporadic colorectal cancer patients
por: Sayagués, José María, et al.
Publicado: (2018)

Modified two‐dimensional response as surrogate marker of overall survival in patients with metastatic colorectal cancer
por: Nakayama, Goro, et al.
Publicado: (2016)

Obstructive Sleep Apnea Worsens Progression-Free and Overall Survival in Human Metastatic Colorectal Carcinoma
por: Lacedonia, Donato, et al.
Publicado: (2021)

Association between Altered Oncogenic Signaling Pathways and Overall Survival of Patients with Metastatic Colorectal Cancer
por: Huang, Yi-Hsuan, et al.
Publicado: (2021)

Mapping of Genetic Abnormalities of Primary Tumours from Metastatic CRC by High-Resolution SNP Arrays
por: Sayagués, José María, et al.
Publicado: (2010)

Severe Hyponatremia Masking Central Diabetes Insipidus in a Patient with a Lung Adenocarcinoma
por: Terán Brage, Eduardo, et al.
Publicado: (2022)

The liver Metastatic Adenocarcinoma of Colorectal Cancer With Synchronous Isolated Hepatic Tuberculosis
por: Hafezi Ahmadi, Mohammadreza, et al.
Publicado: (2013)

Correction: Comparative Genomic Analysis of Primary and Synchronous Metastatic Colorectal Cancers
Publicado: (2015)

Overall survival prediction in metastatic castration-resistant prostate cancer treated with radium-223
por: Vidal, Monica, et al.
Publicado: (2020)

Baseline Quality of Life is a Strong and Independent Prognostic Factor for Overall Survival in Metastatic Colorectal Cancer
por: McGarrah, Patrick, et al.
Publicado: (2023)

Monitoring changes in circulating tumour cells as a prognostic indicator of overall survival and treatment response in patients with metastatic melanoma
por: Klinac, Dragana, et al.
Publicado: (2014)

Angiogenesis-related protein expression in bevacizumab-treated metastatic colorectal cancer: NOTCH1 detrimental to overall survival
por: Paiva, Tadeu Ferreira, et al.
Publicado: (2015)

Erratum to development and validation of an individualized gene expression-based signature to predict overall survival in metastatic colorectal cancer
Publicado: (2022)

Non-transplant patients with haematologic malignancies have better survival outcome than recipients of haematopoietic stem cell transplant (HSCT) after admission to intensive care unit (ICU)
por: Corcia Palomo, Y, et al.
Publicado: (2015)

Sex differences in adults with acute myeloid leukemia and the impact of sex on overall survival
por: Stabellini, Nickolas, et al.
Publicado: (2022)

Molecular Characterization of Circulating Tumor Cells in Human Metastatic Colorectal Cancer
por: Barbazán, Jorge, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_385titai2f4i9u1f78fm7k0iu9