Cargando…

Blood-Based Proteomic Profiling Identifies Potential Biomarker Candidates and Pathogenic Pathways in Dementia

Dementia is a progressive and debilitating neurological disease that affects millions of people worldwide. Identifying the minimally invasive biomarkers associated with dementia that could provide insights into the disease pathogenesis, improve early diagnosis, and facilitate the development of effe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ehtewish, Hanan, Mesleh, Areej, Ponirakis, Georgios, De la Fuente, Alberto, Parray, Aijaz, Bensmail, Ilham, Abdesselem, Houari, Ramadan, Marwan, Khan, Shafi, Chandran, Mani, Ayadathil, Raheem, Elsotouhy, Ahmed, Own, Ahmed, Al Hamad, Hanadi, Abdelalim, Essam M., Decock, Julie, Alajez, Nehad M., Albagha, Omar, Thornalley, Paul J., Arredouani, Abdelilah, Malik, Rayaz A., El-Agnaf, Omar M. A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179172/ https://www.ncbi.nlm.nih.gov/pubmed/37175824 http://dx.doi.org/10.3390/ijms24098117

Ejemplares similares

High-throughput autoantibody screening identifies differentially abundant autoantibodies in autism spectrum disorder
por: Mesleh, Areej, et al.
Publicado: (2023)

Blood Proteomics Analysis Reveals Potential Biomarkers and Convergent Dysregulated Pathways in Autism Spectrum Disorder: A Pilot Study
por: Mesleh, Areej, et al.
Publicado: (2023)

Circulating MicroRNA Profiling Identifies Distinct MicroRNA Signatures in Acute Ischemic Stroke and Transient Ischemic Attack Patients
por: Toor, Salman M., et al.
Publicado: (2022)

Identification of distinct circulating microRNAs in acute ischemic stroke patients with type 2 diabetes mellitus
por: Toor, Salman M., et al.
Publicado: (2022)

Diagnostic, Prognostic, and Mechanistic Biomarkers of Diabetes Mellitus-Associated Cognitive Decline
por: Ehtewish, Hanan, et al.
Publicado: (2022)

Identification of Novel Circulating miRNAs in Patients with Acute Ischemic Stroke
por: Aldous, Eman K., et al.
Publicado: (2022)

Increase in repulsive guidance molecule-a (RGMa) in lacunar and cortical stroke patients is related to the severity of the insult
por: Parray, Aijaz, et al.
Publicado: (2022)

Uncovering a neurological protein signature for severe COVID-19
por: El-Agnaf, Omar, et al.
Publicado: (2023)

Auto-immunoproteomics analysis of COVID-19 ICU patients revealed increased levels of autoantibodies related to the male reproductive system
por: Schmidt, Frank, et al.
Publicado: (2023)

Structural and Biophysical Characterization of Stable Alpha-Synuclein Oligomers
por: Vaikath, Nishant, et al.
Publicado: (2022)

Targeted MicroRNA Profiling Reveals That Exendin-4 Modulates the Expression of Several MicroRNAs to Reduce Steatosis in HepG2 Cells
por: Khalifa, Olfa, et al.
Publicado: (2023)

Transcriptome profiling and network enrichment analyses identify subtype-specific therapeutic gene targets for breast cancer and their microRNA regulatory networks
por: Elango, Ramesh, et al.
Publicado: (2023)

Paving the Way toward Personalized Medicine: Current Advances and Challenges in Multi-OMICS Approach in Autism Spectrum Disorder for Biomarkers Discovery and Patient Stratification
por: Mesleh, Areej G., et al.
Publicado: (2021)

Identification of a Gene Panel Predictive of Triple-Negative Breast Cancer Response to Neoadjuvant Chemotherapy Employing Transcriptomic and Functional Validation
por: Vishnubalaji, Radhakrishnan, et al.
Publicado: (2022)

A Rare Case of Choroid Plexus Papilloma of the Third Ventricle in an Adult
por: Shah, Mohammed Hamza, et al.
Publicado: (2020)

The triglyceride glucose-waist-to-height ratio outperforms obesity and other triglyceride-related parameters in detecting prediabetes in normal-weight Qatari adults: A cross-sectional study
por: Al Akl, Neyla S., et al.
Publicado: (2023)

Critical illness-associated cerebral microbleeds in COVID-19
por: Vattoth, Surjith, et al.
Publicado: (2020)

DNAJB3 attenuates metabolic stress and promotes glucose uptake by eliciting Glut4 translocation
por: Arredouani, Abdelilah, et al.
Publicado: (2019)

Abnormal corneal nerve morphology and brain volume in patients with schizophrenia
por: Ponirakis, Georgios, et al.
Publicado: (2022)

Corneal nerve loss predicts dementia in patients with mild cognitive impairment
por: Ponirakis, Georgios, et al.
Publicado: (2023)

Simple risk score to screen for prediabetes: A cross‐sectional study from the Qatar Biobank cohort
por: Abbas, Mostafa, et al.
Publicado: (2020)

T13. CORNEAL CONFOCAL MICROSCOPY DETECTS NEURAL CHANGES IN SCHIZOPHRENIA
por: Woodruff, Peter, et al.
Publicado: (2020)

Association of corneal nerve fiber measures with cognitive function in dementia
por: Ponirakis, Georgios, et al.
Publicado: (2019)

Loss of corneal nerves and brain volume in mild cognitive impairment and dementia
por: Ponirakis, Georgios, et al.
Publicado: (2022)

Platelet–Neutrophil Association in NETs-Rich Areas in the Retrieved AIS Patient Thrombi
por: Pir, Ghulam Jeelani, et al.
Publicado: (2022)

Using Unstated Cases to Correct for COVID-19 Pandemic Outbreak and Its Impact on Easing the Intervention for Qatar
por: Sallahi, Narjiss, et al.
Publicado: (2021)

Greater and More Focused Measures Are Needed to Tackle Diabetes and Obesity Epidemics in the Nations of the Gulf Cooperation Council
por: Arredouani, Abdelilah
Publicado: (2021)

Editorial: An approach of brain derived extracellular vesicles in diagnosis and prognosis of brain pathologies
por: Qadri, Shahnaz, et al.
Publicado: (2022)

Investigating the presence of doubly phosphorylated α‐synuclein at tyrosine 125 and serine 129 in idiopathic Lewy body diseases
por: Fayyad, Muneera, et al.
Publicado: (2020)

Genome-wide differential expression profiling of long non-coding RNAs in FOXA2 knockout iPSC-derived pancreatic cells
por: Elsayed, Ahmed K., et al.
Publicado: (2023)

Large-Scale Analysis of Gene Expression Data Reveals a Novel Gene Expression Signature Associated with Colorectal Cancer Distant Recurrence
por: Alajez, Nehad M.
Publicado: (2016)

Significance of BMI1 and FSCN1 Expression in Colorectal Cancer
por: Alajez, Nehad M.
Publicado: (2016)

COVID-19: complexity of disease severity revealed by systemic and localized single cell immune atlas
por: Alajez, Nehad M.
Publicado: (2021)

Corneal Nerve and Brain Imaging in Mild Cognitive Impairment and Dementia
por: Al-Janahi, Eiman, et al.
Publicado: (2020)

Association of Cerebral Ischemia With Corneal Nerve Loss and Brain Atrophy in MCI and Dementia
por: Ponirakis, Georgios, et al.
Publicado: (2021)

The impact of enteric coating of aspirin on aspirin responsiveness in patients with suspected or newly diagnosed ischemic stroke: prospective cohort study: results from the (ECASIS) study
por: Elshafei, Mohamed Nabil, et al.
Publicado: (2022)

Fibrillar form of α-synuclein-specific scFv antibody inhibits α-synuclein seeds induced aggregation and toxicity
por: Gupta, Vijay, et al.
Publicado: (2020)

Corneal nerve loss in patients with TIA and acute ischemic stroke in relation to circulating markers of inflammation and vascular integrity
por: Khan, Adnan, et al.
Publicado: (2022)

Spectrum of neuroimaging findings in COVID-19
por: El Beltagi, Ahmed H, et al.
Publicado: (2021)

iPSC-Derived Pancreatic Progenitors Lacking FOXA2 Reveal Alterations in miRNA Expression Targeting Key Pancreatic Genes
por: Aldous, Noura, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_jm4qan2opr1s72nh6to74pn6j1