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Heck Macrocyclization in Forging Non-Natural Large Rings including Macrocyclic Drugs

The intramolecular Heck reaction is a well-established strategy for natural product total synthesis. When constructing large rings, this reaction is also referred to as Heck macrocyclization, which has proved a viable avenue to access diverse naturally occurring macrocycles. Less noticed but likewis...

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Detalles Bibliográficos
Autores principales: Cai, Jiayou, Sun, Bin, Yu, Siqi, Zhang, Han, Zhang, Weicheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179193/
https://www.ncbi.nlm.nih.gov/pubmed/37175956
http://dx.doi.org/10.3390/ijms24098252