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Multiple Dosing and Preactivation of Mesenchymal Stromal Cells Enhance Efficacy in Established Pneumonia Induced by Antimicrobial-Resistant Klebsiella pneumoniae in Rodents

Antimicrobial-resistant (AMR) bacteria, such as Klebsiella species, are an increasingly common cause of hospital-acquired pneumonia, resulting in high mortality and morbidity. Harnessing the host immune response to AMR bacterial infection using mesenchymal stem cells (MSCs) is a promising approach t...

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Detalles Bibliográficos
Autores principales: Byrnes, Declan, Masterson, Claire H., Gonzales, Hector E., McCarthy, Sean D., O’Toole, Daniel P., Laffey, John G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179238/
https://www.ncbi.nlm.nih.gov/pubmed/37175761
http://dx.doi.org/10.3390/ijms24098055