Cargando…

First-Line Combination Treatment with Low-Dose Bipolar Drugs for ABCB1-Overexpressing Drug-Resistant Cancer Populations

Tumors include a heterogeneous population, of which a small proportion includes drug-resistant cancer (stem) cells. In drug-sensitive cancer populations, first-line chemotherapy reduces tumor volume via apoptosis. However, it stimulates drug-resistant cancer populations and finally results in tumor...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yoon, Sungpil, Kim, Hyung Sik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179254/ https://www.ncbi.nlm.nih.gov/pubmed/37176096 http://dx.doi.org/10.3390/ijms24098389

Ejemplares similares

Low-Dose Rifabutin Increases Cytotoxicity in Antimitotic-Drug-Treated Resistant Cancer Cells by Exhibiting Strong P-gp-Inhibitory Activity
por: Lee, Ji Sun, et al.
Publicado: (2022)

Contribution of Cancer-Targeting Drugs toward Faster Clinical Application
por: Yoon, Sungpil, et al.
Publicado: (2022)

Editorial: FDA-Approved Drug Repositioning for P-Glycoprotein Overexpressing Resistant Cancer
por: Yoon, Sungpil, et al.
Publicado: (2021)

Erdafitinib Resensitizes ABCB1-Overexpressing Multidrug-Resistant Cancer Cells to Cytotoxic Anticancer Drugs
por: Wu, Chung-Pu, et al.
Publicado: (2020)

Sapitinib Reverses Anticancer Drug Resistance in Colon Cancer Cells Overexpressing the ABCB1 Transporter
por: Gao, Hai-Ling, et al.
Publicado: (2020)

JAK2 Inhibitor, Fedratinib, Inhibits P-gp Activity and Co-Treatment Induces Cytotoxicity in Antimitotic Drug-Treated P-gp Overexpressing Resistant KBV20C Cancer Cells
por: Oh, Yunmoon, et al.
Publicado: (2022)

Overexpression of microRNA-24 increases the sensitivity to paclitaxel in drug-resistant breast carcinoma cell lines via targeting ABCB9
por: Gong, Jian-Ping, et al.
Publicado: (2016)

Sitravatinib Sensitizes ABCB1- and ABCG2-Overexpressing Multidrug-Resistant Cancer Cells to Chemotherapeutic Drugs
por: Wu, Chung-Pu, et al.
Publicado: (2020)

Terconazole, an Azole Antifungal Drug, Increases Cytotoxicity in Antimitotic Drug-Treated Resistant Cancer Cells with Substrate-Specific P-gp Inhibitory Activity
por: Lee, Ji Sun, et al.
Publicado: (2022)

L1210 Cells Overexpressing ABCB1 Drug Transporters Are Resistant to Inhibitors of the N- and O-glycosylation of Proteins
por: Pavlikova, Lucia, et al.
Publicado: (2017)

ABCB1 Polymorphisms and Drug-Resistant Epilepsy in a Tunisian Population
por: Chouchi, Malek, et al.
Publicado: (2019)

Tepoxalin increases chemotherapy efficacy in drug-resistant breast cancer cells overexpressing the multidrug transporter gene ABCB1
por: McQuerry, Jasmine A., et al.
Publicado: (2021)

Drug resistance in epilepsy and the ABCB1 gene: The clinical perspective
por: Das, Abhijit, et al.
Publicado: (2011)

ABCB1 Overexpression Is a Key Initiator of Resistance to Tyrosine Kinase Inhibitors in CML Cell Lines
por: Eadie, Laura N., et al.
Publicado: (2016)

Low-Dose Crizotinib, a Tyrosine Kinase Inhibitor, Highly and Specifically Sensitizes P-Glycoprotein-Overexpressing Chemoresistant Cancer Cells Through Induction of Late Apoptosis in vivo and in vitro
por: Kim, Kyeong Seok, et al.
Publicado: (2020)

A role for ABCB1 in prognosis, invasion and drug resistance in ependymoma
por: Sabnis, Durgagauri H., et al.
Publicado: (2019)

Bufalin reverses ABCB1-mediated drug resistance in colorectal cancer
por: Yuan, Ze-Ting, et al.
Publicado: (2017)

Antimicrobial Peptide Reverses ABCB1-Mediated Chemotherapeutic Drug Resistance
por: Luo, Xiaofang, et al.
Publicado: (2020)

Drug Resistance in Medulloblastoma Is Driven by YB-1, ABCB1 and a Seven-Gene Drug Signature
por: Taylor, Louisa, et al.
Publicado: (2023)

Generation of a homozygous mutant drug transporter (ABCB1) knockout line in the sea urchin Lytechinus pictus
por: Vyas, Himanshu, et al.
Publicado: (2022)

Drug resistance to paclitaxel is not only associated with ABCB1 mRNA expression but also with drug accumulation in intracellular compartments in human lung cancer cell lines
por: SHIMOMURA, MASANORI, et al.
Publicado: (2011)

ABCB1 and ABCG2 Overexpression Mediates Resistance to the Phosphatidylinositol 3-Kinase Inhibitor HS-173 in Cancer Cell Lines
por: Wu, Chung-Pu, et al.
Publicado: (2023)

Overexpressed ABCB1 Induces Olaparib-Taxane Cross-Resistance in Advanced Prostate Cancer()
por: Lombard, Alan P, et al.
Publicado: (2019)

Rutaecarpine Increases Anticancer Drug Sensitivity in Drug-Resistant Cells through MARCH8-Dependent ABCB1 Degradation
por: Zou, Tingting, et al.
Publicado: (2021)

Impact of the ABCB1 Drug Resistance Gene on the Risk Factors of Patients with COVID-19 and Its Relationship with the Drugs Used
por: Olarte Carrillo, Irma, et al.
Publicado: (2022)

Lazertinib improves the efficacy of chemotherapeutic drugs in ABCB1 or ABCG2 overexpression cancer cells in vitro, in vivo, and ex vivo
por: Fan, Yingfang, et al.
Publicado: (2022)

Tetrandrine Interaction with ABCB1 Reverses Multidrug Resistance in Cancer Cells Through Competition with Anti-Cancer Drugs Followed by Downregulation of ABCB1 Expression
por: Liao, Dan, et al.
Publicado: (2019)

Epigenetic modulation of the drug resistance genes MGMT, ABCB1 and ABCG2 in glioblastoma multiforme
por: Oberstadt, Moritz C, et al.
Publicado: (2013)

Semi-synthetic ocotillol analogues as selective ABCB1-mediated drug resistance reversal agents
por: Zhang, Yun-Kai, et al.
Publicado: (2015)

Targeting ABCB1 (MDR1) in multi-drug resistant osteosarcoma cells using the CRISPR-Cas9 system to reverse drug resistance
por: Liu, Tang, et al.
Publicado: (2016)

The Selective Class IIa Histone Deacetylase Inhibitor TMP195 Resensitizes ABCB1- and ABCG2-Overexpressing Multidrug-Resistant Cancer Cells to Cytotoxic Anticancer Drugs
por: Wu, Chung-Pu, et al.
Publicado: (2019)

Differential expression of ABCB5 in BRAF inhibitor-resistant melanoma cell lines
por: Xiao, Jingjing, et al.
Publicado: (2018)

Clinically Relevant Transmitted Drug Resistance to First Line Antiretroviral Drugs and Implications for Recommendations
por: Monge, Susana, et al.
Publicado: (2014)

Overexpression of Multidrug Resistance Protein Gene in Human Cancer Cell Lines Selected for Drug Resistance to Epipodophyllotoxins
por: Koike, Koji, et al.
Publicado: (1996)

ABCB1 Gene C3435T Polymorphism and Drug Resistance in Epilepsy: Evidence Based on 8604 Subjects
por: Li, Shu-xia, et al.
Publicado: (2015)

Multiple ABCB1 transcriptional fusions in drug resistant high-grade serous ovarian and breast cancer
por: Christie, Elizabeth L., et al.
Publicado: (2019)

Degradation of P-glycoprotein by pristimerin contributes to overcoming ABCB1-mediated chemotherapeutic drug resistance in vitro
por: Yan, Yan-Yan, et al.
Publicado: (2017)

The new allosteric inhibitor asciminib is susceptible to resistance mediated by ABCB1 and ABCG2 overexpression in vitro
por: Eadie, Laura N., et al.
Publicado: (2018)

Carfilzomib resistance due to ABCB1/MDR1 overexpression is overcome by nelfinavir and lopinavir in multiple myeloma
por: Besse, A, et al.
Publicado: (2018)

Overexpression of ABCB1 Transporter Confers Resistance to mTOR Inhibitor WYE-354 in Cancer Cells
por: Wang, Jingqiu, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_chu92ht05n4qakp389j8c30cq2