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Alpha-Deoxyguanosine to Reshape the Alpha-Thrombin Binding Aptamer

Modification of DNA aptamers is aimed at increasing their thermodynamic stability, and improving affinity and resistance to biodegradation. G-quadruplex DNA aptamers are a family of affinity ligands that form non-canonical DNA assemblies based on a G-tetrads stack. Modification of the quadruplex cor...

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Detalles Bibliográficos
Autores principales:	Kolganova, Natalia A., Tsvetkov, Vladimir B., Stomakhin, Andrey A., Surzhikov, Sergei A., Timofeev, Edward N., Varizhuk, Irina V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179326/ https://www.ncbi.nlm.nih.gov/pubmed/37176113 http://dx.doi.org/10.3390/ijms24098406

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