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High-Resolution Single-Shot Fast Spin-Echo MR Imaging with Deep Learning Reconstruction Algorithm Can Improve Repeatability and Reproducibility of Follicle Counting

Objective: To investigate the diagnostic performance of high-resolution single-shot fast spin-echo (SSFSE) imaging with deep learning (DL) reconstruction algorithm on follicle counting and compare it with original SSFSE images and conventional fast spin-echo (FSE) images. Methods: This study include...

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Autores principales: Yang, Renjie, Zou, Yujie, Liu, Weiyin (Vivian), Liu, Changsheng, Wen, Zhi, Li, Liang, Sun, Chenyu, Hu, Min, Zha, Yunfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179356/
https://www.ncbi.nlm.nih.gov/pubmed/37176674
http://dx.doi.org/10.3390/jcm12093234
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author Yang, Renjie
Zou, Yujie
Liu, Weiyin (Vivian)
Liu, Changsheng
Wen, Zhi
Li, Liang
Sun, Chenyu
Hu, Min
Zha, Yunfei
author_facet Yang, Renjie
Zou, Yujie
Liu, Weiyin (Vivian)
Liu, Changsheng
Wen, Zhi
Li, Liang
Sun, Chenyu
Hu, Min
Zha, Yunfei
author_sort Yang, Renjie
collection PubMed
description Objective: To investigate the diagnostic performance of high-resolution single-shot fast spin-echo (SSFSE) imaging with deep learning (DL) reconstruction algorithm on follicle counting and compare it with original SSFSE images and conventional fast spin-echo (FSE) images. Methods: This study included 20 participants (40 ovaries) with clinically confirmed polycystic ovary syndrome (PCOS) who underwent high-resolution ovary MRI, including three-plane T2-weighted FSE sequences and slice-matched T2-weighted SSFSE sequences. A DL reconstruction algorithm was applied to the SSFSE sequences to generate SSFSE-DL images, and the original SSFSE images were also saved. Subjective evaluations such as the blurring artifacts, subjective noise, and clarity of the follicles on the SSFSE-DL, SSFSE, and conventional FSE images were independently conducted by two observers. Intra-class correlation coefficients and Bland–Altman plots were used to present the repeatability and reproducibility of the follicle number per ovary (FNPO) based on the three types of images. Results: SSFSE-DL images showed less blurring artifact, subjective noise, and better clarity of the follicles than SSFSE and FSE (p < 0.05). For the repeatability of the FNPO, SSFSE-DL showed the highest intra-observer (ICC = 0.930; 95% CI: 0.878–0.962) and inter-observer (ICC = 0.914; 95% CI: 0.843–0.953) agreements. The inter-observer 95% limits of agreement (LOA) for SSFSE-DL, SSFSE, and FSE ranged from −3.7 to 4.5, −4.4 to 7.0, and −7.1 to 7.6, respectively. The intra-observer 95% LOA for SSFSE-DL, SSFSE, and FSE ranged from −3.5 to 4.0, −5.1 to 6.1, and −5.7 to 4.2, respectively. The absolute values of intra-observer and inter-observer differences for SSFSE-DL were significantly lower than those for SSFSE and FSE (p < 0.05). Conclusions: Compared with the original SSFSE images and the conventional FSE images, high-resolution SSFSE images with DL reconstruction algorithm can better display follicles, thus improving FNPO assessment.
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spelling pubmed-101793562023-05-13 High-Resolution Single-Shot Fast Spin-Echo MR Imaging with Deep Learning Reconstruction Algorithm Can Improve Repeatability and Reproducibility of Follicle Counting Yang, Renjie Zou, Yujie Liu, Weiyin (Vivian) Liu, Changsheng Wen, Zhi Li, Liang Sun, Chenyu Hu, Min Zha, Yunfei J Clin Med Article Objective: To investigate the diagnostic performance of high-resolution single-shot fast spin-echo (SSFSE) imaging with deep learning (DL) reconstruction algorithm on follicle counting and compare it with original SSFSE images and conventional fast spin-echo (FSE) images. Methods: This study included 20 participants (40 ovaries) with clinically confirmed polycystic ovary syndrome (PCOS) who underwent high-resolution ovary MRI, including three-plane T2-weighted FSE sequences and slice-matched T2-weighted SSFSE sequences. A DL reconstruction algorithm was applied to the SSFSE sequences to generate SSFSE-DL images, and the original SSFSE images were also saved. Subjective evaluations such as the blurring artifacts, subjective noise, and clarity of the follicles on the SSFSE-DL, SSFSE, and conventional FSE images were independently conducted by two observers. Intra-class correlation coefficients and Bland–Altman plots were used to present the repeatability and reproducibility of the follicle number per ovary (FNPO) based on the three types of images. Results: SSFSE-DL images showed less blurring artifact, subjective noise, and better clarity of the follicles than SSFSE and FSE (p < 0.05). For the repeatability of the FNPO, SSFSE-DL showed the highest intra-observer (ICC = 0.930; 95% CI: 0.878–0.962) and inter-observer (ICC = 0.914; 95% CI: 0.843–0.953) agreements. The inter-observer 95% limits of agreement (LOA) for SSFSE-DL, SSFSE, and FSE ranged from −3.7 to 4.5, −4.4 to 7.0, and −7.1 to 7.6, respectively. The intra-observer 95% LOA for SSFSE-DL, SSFSE, and FSE ranged from −3.5 to 4.0, −5.1 to 6.1, and −5.7 to 4.2, respectively. The absolute values of intra-observer and inter-observer differences for SSFSE-DL were significantly lower than those for SSFSE and FSE (p < 0.05). Conclusions: Compared with the original SSFSE images and the conventional FSE images, high-resolution SSFSE images with DL reconstruction algorithm can better display follicles, thus improving FNPO assessment. MDPI 2023-04-30 /pmc/articles/PMC10179356/ /pubmed/37176674 http://dx.doi.org/10.3390/jcm12093234 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Yang, Renjie
Zou, Yujie
Liu, Weiyin (Vivian)
Liu, Changsheng
Wen, Zhi
Li, Liang
Sun, Chenyu
Hu, Min
Zha, Yunfei
High-Resolution Single-Shot Fast Spin-Echo MR Imaging with Deep Learning Reconstruction Algorithm Can Improve Repeatability and Reproducibility of Follicle Counting
title High-Resolution Single-Shot Fast Spin-Echo MR Imaging with Deep Learning Reconstruction Algorithm Can Improve Repeatability and Reproducibility of Follicle Counting
title_full High-Resolution Single-Shot Fast Spin-Echo MR Imaging with Deep Learning Reconstruction Algorithm Can Improve Repeatability and Reproducibility of Follicle Counting
title_fullStr High-Resolution Single-Shot Fast Spin-Echo MR Imaging with Deep Learning Reconstruction Algorithm Can Improve Repeatability and Reproducibility of Follicle Counting
title_full_unstemmed High-Resolution Single-Shot Fast Spin-Echo MR Imaging with Deep Learning Reconstruction Algorithm Can Improve Repeatability and Reproducibility of Follicle Counting
title_short High-Resolution Single-Shot Fast Spin-Echo MR Imaging with Deep Learning Reconstruction Algorithm Can Improve Repeatability and Reproducibility of Follicle Counting
title_sort high-resolution single-shot fast spin-echo mr imaging with deep learning reconstruction algorithm can improve repeatability and reproducibility of follicle counting
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179356/
https://www.ncbi.nlm.nih.gov/pubmed/37176674
http://dx.doi.org/10.3390/jcm12093234
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