Redox-Cycling “Mitocans” as Effective New Developments in Anticancer Therapy

Our study proposes a pharmacological strategy to target cancerous mitochondria via redox-cycling “mitocans” such as quinone/ascorbate (Q/A) redox-pairs, which makes cancer cells fragile and sensitive without adverse effects on normal cells and tissues. Eleven Q/A redox-pairs were tested on cultured...

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Detalles Bibliográficos
Autores principales: Bakalova, Rumiana, Lazarova, Dessislava, Sumiyoshi, Akira, Shibata, Sayaka, Zhelev, Zhivko, Nikolova, Biliana, Semkova, Severina, Vlaykova, Tatyana, Aoki, Ichio, Higashi, Tatsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179378/
https://www.ncbi.nlm.nih.gov/pubmed/37176145
http://dx.doi.org/10.3390/ijms24098435

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179378/
https://www.ncbi.nlm.nih.gov/pubmed/37176145
http://dx.doi.org/10.3390/ijms24098435

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