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Redox-Cycling “Mitocans” as Effective New Developments in Anticancer Therapy
Our study proposes a pharmacological strategy to target cancerous mitochondria via redox-cycling “mitocans” such as quinone/ascorbate (Q/A) redox-pairs, which makes cancer cells fragile and sensitive without adverse effects on normal cells and tissues. Eleven Q/A redox-pairs were tested on cultured...
Autores principales: | Bakalova, Rumiana, Lazarova, Dessislava, Sumiyoshi, Akira, Shibata, Sayaka, Zhelev, Zhivko, Nikolova, Biliana, Semkova, Severina, Vlaykova, Tatyana, Aoki, Ichio, Higashi, Tatsuya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179378/ https://www.ncbi.nlm.nih.gov/pubmed/37176145 http://dx.doi.org/10.3390/ijms24098435 |
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