Computational and Enzymatic Studies of Sartans in SARS-CoV-2 Spike RBD-ACE2 Binding: The Role of Tetrazole and Perspectives as Antihypertensive and COVID-19 Therapeutics

This study is an extension of current research into a novel class of synthetic antihypertensive drugs referred to as “bisartans”, which are bis-alkylated imidazole derivatives bearing two symmetric anionic biphenyltetrazoles. Research to date indicates that bisartans are superior to commercially ava...

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Detalles Bibliográficos
Autores principales: Kelaidonis, Konstantinos, Ligielli, Irene, Letsios, Spiros, Vidali, Veroniki P., Mavromoustakos, Thomas, Vassilaki, Niki, Moore, Graham J., Hoffmann, Weronika, Węgrzyn, Katarzyna, Ridgway, Harry, Chasapis, Christos T., Matsoukas, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179460/
https://www.ncbi.nlm.nih.gov/pubmed/37176159
http://dx.doi.org/10.3390/ijms24098454

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179460/
https://www.ncbi.nlm.nih.gov/pubmed/37176159
http://dx.doi.org/10.3390/ijms24098454

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