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Flavone and Hydroxyflavones Are Ligands That Bind the Orphan Nuclear Receptor 4A1 (NR4A1)

It was recently reported that the hydroxyflavones quercetin and kaempferol bind the orphan nuclear receptor 4A1 (NR4A1, Nur77) and act as antagonists in cancer cells and tumors, and they inhibit pro-oncogenic NR4A1-regulated genes and pathways. In this study, we investigated the interactions of flav...

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Detalles Bibliográficos
Autores principales:	Lee, Miok, Upadhyay, Srijana, Mariyam, Fuada, Martin, Greg, Hailemariam, Amanuel, Lee, Kyongbum, Jayaraman, Arul, Chapkin, Robert S., Lee, Syng-Ook, Safe, Stephen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179475/ https://www.ncbi.nlm.nih.gov/pubmed/37175855 http://dx.doi.org/10.3390/ijms24098152

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