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Splicing Characterization and Isoform Switch Events in Human Keratinocytes Carrying Oncogenes from High-Risk HPV-16 and Low-Risk HPV-84

Infection of epithelial cells with high-risk HPV (HR-HPV) types, followed by expression of virus oncogenic proteins (E5, E6, and E7), leads to genomic imbalance, suppression of tumor inhibitors, and induction of oncogenes. Low-risk HPV (LR-HPV) may slow the rate at which cervical cancer spreads to a...

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Detalles Bibliográficos
Autores principales: Nasiri-Aghdam, Maryam, Garcia-Chagollan, Mariel, Pereira-Suarez, Ana Laura, Aguilar-Lemarroy, Adriana, Jave-Suarez, Luis Felipe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179494/
https://www.ncbi.nlm.nih.gov/pubmed/37176052
http://dx.doi.org/10.3390/ijms24098347