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Immune and Hereditary Thrombotic Thrombocytopenic Purpura: Can ADAMTS13 Deficiency Alone Explain the Different Clinical Phenotypes?

Thrombotic thrombocytopenic purpura (TTP) is a thrombotic microangiopathy caused by a hereditary or immune-mediated deficiency of the enzyme ADAMTS13 (a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13). TTPs are caused by the following pathophysiological mechanisms: (...

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Detalles Bibliográficos
Autores principales:	Lancellotti, Stefano, Sacco, Monica, Tardugno, Maira, Ferretti, Antonietta, De Cristofaro, Raimondo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179526/ https://www.ncbi.nlm.nih.gov/pubmed/37176552 http://dx.doi.org/10.3390/jcm12093111

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