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Clinical Applications of Optical Coherence Tomography Angiography in Inherited Retinal Diseases: An Up-to-Date Review of the Literature

Optical coherence tomography angiography (OCT-A) is a valuable imaging technique, allowing non-invasive, depth-resolved, motion-contrast, high-resolution images of both retinal and choroidal vascular networks. The imaging capabilities of OCT-A have enhanced our understanding of the retinal and choro...

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Autores principales: Iovino, Claudio, Iodice, Clemente Maria, Pisani, Danila, Damiano, Luciana, Di Iorio, Valentina, Testa, Francesco, Simonelli, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179546/
https://www.ncbi.nlm.nih.gov/pubmed/37176614
http://dx.doi.org/10.3390/jcm12093170
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author Iovino, Claudio
Iodice, Clemente Maria
Pisani, Danila
Damiano, Luciana
Di Iorio, Valentina
Testa, Francesco
Simonelli, Francesca
author_facet Iovino, Claudio
Iodice, Clemente Maria
Pisani, Danila
Damiano, Luciana
Di Iorio, Valentina
Testa, Francesco
Simonelli, Francesca
author_sort Iovino, Claudio
collection PubMed
description Optical coherence tomography angiography (OCT-A) is a valuable imaging technique, allowing non-invasive, depth-resolved, motion-contrast, high-resolution images of both retinal and choroidal vascular networks. The imaging capabilities of OCT-A have enhanced our understanding of the retinal and choroidal alterations that occur in inherited retinal diseases (IRDs), a group of clinically and genetically heterogeneous disorders that may be complicated by several vascular conditions requiring a prompt diagnosis. In this review, we aimed to comprehensively summarize all clinical applications of OCT-A in the diagnosis and management of IRDs, highlighting significant vascular findings on retinitis pigmentosa, Stargardt disease, choroideremia, Best disease and other less common forms of retinal dystrophies. All advantages and limitations of this novel imaging modality will be also discussed.
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spelling pubmed-101795462023-05-13 Clinical Applications of Optical Coherence Tomography Angiography in Inherited Retinal Diseases: An Up-to-Date Review of the Literature Iovino, Claudio Iodice, Clemente Maria Pisani, Danila Damiano, Luciana Di Iorio, Valentina Testa, Francesco Simonelli, Francesca J Clin Med Review Optical coherence tomography angiography (OCT-A) is a valuable imaging technique, allowing non-invasive, depth-resolved, motion-contrast, high-resolution images of both retinal and choroidal vascular networks. The imaging capabilities of OCT-A have enhanced our understanding of the retinal and choroidal alterations that occur in inherited retinal diseases (IRDs), a group of clinically and genetically heterogeneous disorders that may be complicated by several vascular conditions requiring a prompt diagnosis. In this review, we aimed to comprehensively summarize all clinical applications of OCT-A in the diagnosis and management of IRDs, highlighting significant vascular findings on retinitis pigmentosa, Stargardt disease, choroideremia, Best disease and other less common forms of retinal dystrophies. All advantages and limitations of this novel imaging modality will be also discussed. MDPI 2023-04-28 /pmc/articles/PMC10179546/ /pubmed/37176614 http://dx.doi.org/10.3390/jcm12093170 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Iovino, Claudio
Iodice, Clemente Maria
Pisani, Danila
Damiano, Luciana
Di Iorio, Valentina
Testa, Francesco
Simonelli, Francesca
Clinical Applications of Optical Coherence Tomography Angiography in Inherited Retinal Diseases: An Up-to-Date Review of the Literature
title Clinical Applications of Optical Coherence Tomography Angiography in Inherited Retinal Diseases: An Up-to-Date Review of the Literature
title_full Clinical Applications of Optical Coherence Tomography Angiography in Inherited Retinal Diseases: An Up-to-Date Review of the Literature
title_fullStr Clinical Applications of Optical Coherence Tomography Angiography in Inherited Retinal Diseases: An Up-to-Date Review of the Literature
title_full_unstemmed Clinical Applications of Optical Coherence Tomography Angiography in Inherited Retinal Diseases: An Up-to-Date Review of the Literature
title_short Clinical Applications of Optical Coherence Tomography Angiography in Inherited Retinal Diseases: An Up-to-Date Review of the Literature
title_sort clinical applications of optical coherence tomography angiography in inherited retinal diseases: an up-to-date review of the literature
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179546/
https://www.ncbi.nlm.nih.gov/pubmed/37176614
http://dx.doi.org/10.3390/jcm12093170
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