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Enteral Nutrition during Radiotherapy for Oropharyngeal Cancers: Prevalence and Prognostic Factors Based on HPV Status (A GETTEC Study)
Nutritional support during radiotherapy is crucial to tolerating and completing oropharyngeal squamous cell carcinoma (OPSCC) treatment. The impact of HPV status on nutritional support is debated. The objective was to evaluate the rate of Reactive Feeding Tube (RFT) use and determine its prognostic...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179627/ https://www.ncbi.nlm.nih.gov/pubmed/37176609 http://dx.doi.org/10.3390/jcm12093169 |
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author | Culié, Dorian Schiappa, Renaud Pace-Loscos, Tanguy Guelfucci, Bruno Vergez, Sebastien Garrel, Renaud Fakhry, Nicolas Dassonville, Olivier Poissonnet, Gilles Lallemant, Benjamin Sudaka, Anne Saada-Bouzid, Esma Benezery, Karen Temam, Stephane Gorphe, Phillipe Chamorey, Emmanuel Bozec, Alexandre |
author_facet | Culié, Dorian Schiappa, Renaud Pace-Loscos, Tanguy Guelfucci, Bruno Vergez, Sebastien Garrel, Renaud Fakhry, Nicolas Dassonville, Olivier Poissonnet, Gilles Lallemant, Benjamin Sudaka, Anne Saada-Bouzid, Esma Benezery, Karen Temam, Stephane Gorphe, Phillipe Chamorey, Emmanuel Bozec, Alexandre |
author_sort | Culié, Dorian |
collection | PubMed |
description | Nutritional support during radiotherapy is crucial to tolerating and completing oropharyngeal squamous cell carcinoma (OPSCC) treatment. The impact of HPV status on nutritional support is debated. The objective was to evaluate the rate of Reactive Feeding Tube (RFT) use and determine its prognostic factors during definitive radiotherapy for OPSCC. All OPSCC patients treated from 2009 to 2014 were included in this multicentric retrospective study. The impact of tumor p16 status on the risk of RFT was assessed through multivariate analyses. Among the 543 patients, 103 patients required an RFT (19.0%). The use of RFT differed between centers (5% to 32.4%). In multivariate analysis, only tongue base involvement and concurrent chemotherapy were significantly associated with RFT (OR = 2.18 and 3.7, respectively). Tongue base involvement and concomitant chemotherapy were prognostic factors for RFT. HPV status was not a prognostic factor for enteral nutrition during radiotherapy for OPSCC. |
format | Online Article Text |
id | pubmed-10179627 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-101796272023-05-13 Enteral Nutrition during Radiotherapy for Oropharyngeal Cancers: Prevalence and Prognostic Factors Based on HPV Status (A GETTEC Study) Culié, Dorian Schiappa, Renaud Pace-Loscos, Tanguy Guelfucci, Bruno Vergez, Sebastien Garrel, Renaud Fakhry, Nicolas Dassonville, Olivier Poissonnet, Gilles Lallemant, Benjamin Sudaka, Anne Saada-Bouzid, Esma Benezery, Karen Temam, Stephane Gorphe, Phillipe Chamorey, Emmanuel Bozec, Alexandre J Clin Med Article Nutritional support during radiotherapy is crucial to tolerating and completing oropharyngeal squamous cell carcinoma (OPSCC) treatment. The impact of HPV status on nutritional support is debated. The objective was to evaluate the rate of Reactive Feeding Tube (RFT) use and determine its prognostic factors during definitive radiotherapy for OPSCC. All OPSCC patients treated from 2009 to 2014 were included in this multicentric retrospective study. The impact of tumor p16 status on the risk of RFT was assessed through multivariate analyses. Among the 543 patients, 103 patients required an RFT (19.0%). The use of RFT differed between centers (5% to 32.4%). In multivariate analysis, only tongue base involvement and concurrent chemotherapy were significantly associated with RFT (OR = 2.18 and 3.7, respectively). Tongue base involvement and concomitant chemotherapy were prognostic factors for RFT. HPV status was not a prognostic factor for enteral nutrition during radiotherapy for OPSCC. MDPI 2023-04-28 /pmc/articles/PMC10179627/ /pubmed/37176609 http://dx.doi.org/10.3390/jcm12093169 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Culié, Dorian Schiappa, Renaud Pace-Loscos, Tanguy Guelfucci, Bruno Vergez, Sebastien Garrel, Renaud Fakhry, Nicolas Dassonville, Olivier Poissonnet, Gilles Lallemant, Benjamin Sudaka, Anne Saada-Bouzid, Esma Benezery, Karen Temam, Stephane Gorphe, Phillipe Chamorey, Emmanuel Bozec, Alexandre Enteral Nutrition during Radiotherapy for Oropharyngeal Cancers: Prevalence and Prognostic Factors Based on HPV Status (A GETTEC Study) |
title | Enteral Nutrition during Radiotherapy for Oropharyngeal Cancers: Prevalence and Prognostic Factors Based on HPV Status (A GETTEC Study) |
title_full | Enteral Nutrition during Radiotherapy for Oropharyngeal Cancers: Prevalence and Prognostic Factors Based on HPV Status (A GETTEC Study) |
title_fullStr | Enteral Nutrition during Radiotherapy for Oropharyngeal Cancers: Prevalence and Prognostic Factors Based on HPV Status (A GETTEC Study) |
title_full_unstemmed | Enteral Nutrition during Radiotherapy for Oropharyngeal Cancers: Prevalence and Prognostic Factors Based on HPV Status (A GETTEC Study) |
title_short | Enteral Nutrition during Radiotherapy for Oropharyngeal Cancers: Prevalence and Prognostic Factors Based on HPV Status (A GETTEC Study) |
title_sort | enteral nutrition during radiotherapy for oropharyngeal cancers: prevalence and prognostic factors based on hpv status (a gettec study) |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179627/ https://www.ncbi.nlm.nih.gov/pubmed/37176609 http://dx.doi.org/10.3390/jcm12093169 |
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