Self-Renewal and Pluripotency in Osteosarcoma Stem Cells’ Chemoresistance: Notch, Hedgehog, and Wnt/β-Catenin Interplay with Embryonic Markers

Osteosarcoma is a highly malignant bone tumor derived from mesenchymal cells that contains self-renewing cancer stem cells (CSCs), which are responsible for tumor progression and chemotherapy resistance. Understanding the signaling pathways that regulate CSC self-renewal and survival is crucial for...

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Detalles Bibliográficos
Autores principales: Martins-Neves, Sara R., Sampaio-Ribeiro, Gabriela, Gomes, Célia M. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179672/
https://www.ncbi.nlm.nih.gov/pubmed/37176108
http://dx.doi.org/10.3390/ijms24098401

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179672/
https://www.ncbi.nlm.nih.gov/pubmed/37176108
http://dx.doi.org/10.3390/ijms24098401

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