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Fundamental Aspects of Skin Cancer Drugs via Degree-Based Chemical Bonding Topological Descriptors
Due to significant advancements being made in the field of drug design, the use of topological descriptors remains the primary approach. When combined with QSPR models, descriptors illustrate a molecule’s chemical properties numerically. Numbers relating to chemical composition topological indices a...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179816/ https://www.ncbi.nlm.nih.gov/pubmed/37175093 http://dx.doi.org/10.3390/molecules28093684 |
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author | Khan, Abdul Rauf Awan, Nadeem ul Hassan Ghani, Muhammad Usman Eldin, Sayed M. Karamti, Hanen Jawhari, Ahmed H. Mukhrish, Yousef E. |
author_facet | Khan, Abdul Rauf Awan, Nadeem ul Hassan Ghani, Muhammad Usman Eldin, Sayed M. Karamti, Hanen Jawhari, Ahmed H. Mukhrish, Yousef E. |
author_sort | Khan, Abdul Rauf |
collection | PubMed |
description | Due to significant advancements being made in the field of drug design, the use of topological descriptors remains the primary approach. When combined with QSPR models, descriptors illustrate a molecule’s chemical properties numerically. Numbers relating to chemical composition topological indices are structures that link chemical composition to physical characteristics. This research concentrates on the analysis of curvilinear regression models and degree-based topological descriptors for thirteen skin cancer drugs. The physicochemical characteristics of the skin cancer drugs are examined while regression models are built for computed index values. An analysis is performed for several significant results based on the acquired data. |
format | Online Article Text |
id | pubmed-10179816 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-101798162023-05-13 Fundamental Aspects of Skin Cancer Drugs via Degree-Based Chemical Bonding Topological Descriptors Khan, Abdul Rauf Awan, Nadeem ul Hassan Ghani, Muhammad Usman Eldin, Sayed M. Karamti, Hanen Jawhari, Ahmed H. Mukhrish, Yousef E. Molecules Article Due to significant advancements being made in the field of drug design, the use of topological descriptors remains the primary approach. When combined with QSPR models, descriptors illustrate a molecule’s chemical properties numerically. Numbers relating to chemical composition topological indices are structures that link chemical composition to physical characteristics. This research concentrates on the analysis of curvilinear regression models and degree-based topological descriptors for thirteen skin cancer drugs. The physicochemical characteristics of the skin cancer drugs are examined while regression models are built for computed index values. An analysis is performed for several significant results based on the acquired data. MDPI 2023-04-24 /pmc/articles/PMC10179816/ /pubmed/37175093 http://dx.doi.org/10.3390/molecules28093684 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Khan, Abdul Rauf Awan, Nadeem ul Hassan Ghani, Muhammad Usman Eldin, Sayed M. Karamti, Hanen Jawhari, Ahmed H. Mukhrish, Yousef E. Fundamental Aspects of Skin Cancer Drugs via Degree-Based Chemical Bonding Topological Descriptors |
title | Fundamental Aspects of Skin Cancer Drugs via Degree-Based Chemical Bonding Topological Descriptors |
title_full | Fundamental Aspects of Skin Cancer Drugs via Degree-Based Chemical Bonding Topological Descriptors |
title_fullStr | Fundamental Aspects of Skin Cancer Drugs via Degree-Based Chemical Bonding Topological Descriptors |
title_full_unstemmed | Fundamental Aspects of Skin Cancer Drugs via Degree-Based Chemical Bonding Topological Descriptors |
title_short | Fundamental Aspects of Skin Cancer Drugs via Degree-Based Chemical Bonding Topological Descriptors |
title_sort | fundamental aspects of skin cancer drugs via degree-based chemical bonding topological descriptors |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179816/ https://www.ncbi.nlm.nih.gov/pubmed/37175093 http://dx.doi.org/10.3390/molecules28093684 |
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