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Fundamental Aspects of Skin Cancer Drugs via Degree-Based Chemical Bonding Topological Descriptors

Due to significant advancements being made in the field of drug design, the use of topological descriptors remains the primary approach. When combined with QSPR models, descriptors illustrate a molecule’s chemical properties numerically. Numbers relating to chemical composition topological indices a...

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Autores principales: Khan, Abdul Rauf, Awan, Nadeem ul Hassan, Ghani, Muhammad Usman, Eldin, Sayed M., Karamti, Hanen, Jawhari, Ahmed H., Mukhrish, Yousef E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179816/
https://www.ncbi.nlm.nih.gov/pubmed/37175093
http://dx.doi.org/10.3390/molecules28093684
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author Khan, Abdul Rauf
Awan, Nadeem ul Hassan
Ghani, Muhammad Usman
Eldin, Sayed M.
Karamti, Hanen
Jawhari, Ahmed H.
Mukhrish, Yousef E.
author_facet Khan, Abdul Rauf
Awan, Nadeem ul Hassan
Ghani, Muhammad Usman
Eldin, Sayed M.
Karamti, Hanen
Jawhari, Ahmed H.
Mukhrish, Yousef E.
author_sort Khan, Abdul Rauf
collection PubMed
description Due to significant advancements being made in the field of drug design, the use of topological descriptors remains the primary approach. When combined with QSPR models, descriptors illustrate a molecule’s chemical properties numerically. Numbers relating to chemical composition topological indices are structures that link chemical composition to physical characteristics. This research concentrates on the analysis of curvilinear regression models and degree-based topological descriptors for thirteen skin cancer drugs. The physicochemical characteristics of the skin cancer drugs are examined while regression models are built for computed index values. An analysis is performed for several significant results based on the acquired data.
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spelling pubmed-101798162023-05-13 Fundamental Aspects of Skin Cancer Drugs via Degree-Based Chemical Bonding Topological Descriptors Khan, Abdul Rauf Awan, Nadeem ul Hassan Ghani, Muhammad Usman Eldin, Sayed M. Karamti, Hanen Jawhari, Ahmed H. Mukhrish, Yousef E. Molecules Article Due to significant advancements being made in the field of drug design, the use of topological descriptors remains the primary approach. When combined with QSPR models, descriptors illustrate a molecule’s chemical properties numerically. Numbers relating to chemical composition topological indices are structures that link chemical composition to physical characteristics. This research concentrates on the analysis of curvilinear regression models and degree-based topological descriptors for thirteen skin cancer drugs. The physicochemical characteristics of the skin cancer drugs are examined while regression models are built for computed index values. An analysis is performed for several significant results based on the acquired data. MDPI 2023-04-24 /pmc/articles/PMC10179816/ /pubmed/37175093 http://dx.doi.org/10.3390/molecules28093684 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Khan, Abdul Rauf
Awan, Nadeem ul Hassan
Ghani, Muhammad Usman
Eldin, Sayed M.
Karamti, Hanen
Jawhari, Ahmed H.
Mukhrish, Yousef E.
Fundamental Aspects of Skin Cancer Drugs via Degree-Based Chemical Bonding Topological Descriptors
title Fundamental Aspects of Skin Cancer Drugs via Degree-Based Chemical Bonding Topological Descriptors
title_full Fundamental Aspects of Skin Cancer Drugs via Degree-Based Chemical Bonding Topological Descriptors
title_fullStr Fundamental Aspects of Skin Cancer Drugs via Degree-Based Chemical Bonding Topological Descriptors
title_full_unstemmed Fundamental Aspects of Skin Cancer Drugs via Degree-Based Chemical Bonding Topological Descriptors
title_short Fundamental Aspects of Skin Cancer Drugs via Degree-Based Chemical Bonding Topological Descriptors
title_sort fundamental aspects of skin cancer drugs via degree-based chemical bonding topological descriptors
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179816/
https://www.ncbi.nlm.nih.gov/pubmed/37175093
http://dx.doi.org/10.3390/molecules28093684
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