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Review of Characteristics and Analytical Methods for Determination of Thiabendazole

Thiabendazole (TBZ) is a fungicide and anthelmintic drug commonly found in food products. Due to its toxicity and potential carcinogenicity, its determination in various samples is important for public health. Different analytical methods can be used to determine the presence and concentration of TB...

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Autores principales: Budetić, Mateja, Kopf, Doris, Dandić, Andrea, Samardžić, Mirela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179875/
https://www.ncbi.nlm.nih.gov/pubmed/37175335
http://dx.doi.org/10.3390/molecules28093926
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author Budetić, Mateja
Kopf, Doris
Dandić, Andrea
Samardžić, Mirela
author_facet Budetić, Mateja
Kopf, Doris
Dandić, Andrea
Samardžić, Mirela
author_sort Budetić, Mateja
collection PubMed
description Thiabendazole (TBZ) is a fungicide and anthelmintic drug commonly found in food products. Due to its toxicity and potential carcinogenicity, its determination in various samples is important for public health. Different analytical methods can be used to determine the presence and concentration of TBZ in samples. Liquid chromatography (LC) and its subtypes, high-performance liquid chromatography (HPLC) and ultra-high-performance liquid chromatography (UHPLC), are the most commonly used methods for TBZ determination representing 19%, 18%, and 18% of the described methods, respectively. Surface-enhanced Raman spectroscopy (SERS) and fluorimetry are two more methods widely used for TBZ determination, representing 13% and 12% of the described methods, respectively. In this review, a number of methods for TBZ determination are described, but due to their limitations, there is a high potential for the further improvement and development of each method in order to obtain a simple, precise, and accurate method that can be used for routine analysis.
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spelling pubmed-101798752023-05-13 Review of Characteristics and Analytical Methods for Determination of Thiabendazole Budetić, Mateja Kopf, Doris Dandić, Andrea Samardžić, Mirela Molecules Review Thiabendazole (TBZ) is a fungicide and anthelmintic drug commonly found in food products. Due to its toxicity and potential carcinogenicity, its determination in various samples is important for public health. Different analytical methods can be used to determine the presence and concentration of TBZ in samples. Liquid chromatography (LC) and its subtypes, high-performance liquid chromatography (HPLC) and ultra-high-performance liquid chromatography (UHPLC), are the most commonly used methods for TBZ determination representing 19%, 18%, and 18% of the described methods, respectively. Surface-enhanced Raman spectroscopy (SERS) and fluorimetry are two more methods widely used for TBZ determination, representing 13% and 12% of the described methods, respectively. In this review, a number of methods for TBZ determination are described, but due to their limitations, there is a high potential for the further improvement and development of each method in order to obtain a simple, precise, and accurate method that can be used for routine analysis. MDPI 2023-05-06 /pmc/articles/PMC10179875/ /pubmed/37175335 http://dx.doi.org/10.3390/molecules28093926 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Budetić, Mateja
Kopf, Doris
Dandić, Andrea
Samardžić, Mirela
Review of Characteristics and Analytical Methods for Determination of Thiabendazole
title Review of Characteristics and Analytical Methods for Determination of Thiabendazole
title_full Review of Characteristics and Analytical Methods for Determination of Thiabendazole
title_fullStr Review of Characteristics and Analytical Methods for Determination of Thiabendazole
title_full_unstemmed Review of Characteristics and Analytical Methods for Determination of Thiabendazole
title_short Review of Characteristics and Analytical Methods for Determination of Thiabendazole
title_sort review of characteristics and analytical methods for determination of thiabendazole
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179875/
https://www.ncbi.nlm.nih.gov/pubmed/37175335
http://dx.doi.org/10.3390/molecules28093926
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