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Charge Transfer Complex of Lorlatinib with Chloranilic Acid: Characterization and Application to the Development of a Novel 96-Microwell Spectrophotometric Assay with High Throughput

Lorlatinib (LRL) is the first drug of the third generation of anaplastic lymphoma kinase (ALK) inhibitors used a first-line treatment of non-small cell lung cancer (NSCLC). This study describes, for the first time, the investigations for the formation of a charge transfer complex (CTC) between LRL,...

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Detalles Bibliográficos
Autores principales: Darwish, Hany W., Darwish, Ibrahim A., Ali, Awadh M., Almutairi, Halah S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179897/
https://www.ncbi.nlm.nih.gov/pubmed/37175262
http://dx.doi.org/10.3390/molecules28093852