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Immunomodulatory, Anti-Inflammatory, and Anti-Cancer Properties of Ginseng: A Pharmacological Update

Ginseng, a medicinal plant of the genus Panax, boasts a rich historical record of usage that dates back to the Paleolithic period. This botanical is extensively acknowledged and consumed in Eastern countries for its therapeutic properties, and, in Western countries, it is becoming increasingly popul...

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Autores principales: Valdés-González, Jose Antonio, Sánchez, Marta, Moratilla-Rivera, Ignacio, Iglesias, Irene, Gómez-Serranillos, María Pilar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10180039/
https://www.ncbi.nlm.nih.gov/pubmed/37175273
http://dx.doi.org/10.3390/molecules28093863
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author Valdés-González, Jose Antonio
Sánchez, Marta
Moratilla-Rivera, Ignacio
Iglesias, Irene
Gómez-Serranillos, María Pilar
author_facet Valdés-González, Jose Antonio
Sánchez, Marta
Moratilla-Rivera, Ignacio
Iglesias, Irene
Gómez-Serranillos, María Pilar
author_sort Valdés-González, Jose Antonio
collection PubMed
description Ginseng, a medicinal plant of the genus Panax, boasts a rich historical record of usage that dates back to the Paleolithic period. This botanical is extensively acknowledged and consumed in Eastern countries for its therapeutic properties, and, in Western countries, it is becoming increasingly popular as a remedy for fatigue and asthenia. This review provides an update on current research pertaining to ginseng and its isolated compounds, namely, ginsenosides and polysaccharides. The primary focus is on three crucial pharmacological activities, namely, immunomodulation, anti-inflammatory, and anti-cancer effects. The review encompasses studies on both isolated compounds and various ginseng extracts obtained from the root, leaves, and berries.
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spelling pubmed-101800392023-05-13 Immunomodulatory, Anti-Inflammatory, and Anti-Cancer Properties of Ginseng: A Pharmacological Update Valdés-González, Jose Antonio Sánchez, Marta Moratilla-Rivera, Ignacio Iglesias, Irene Gómez-Serranillos, María Pilar Molecules Review Ginseng, a medicinal plant of the genus Panax, boasts a rich historical record of usage that dates back to the Paleolithic period. This botanical is extensively acknowledged and consumed in Eastern countries for its therapeutic properties, and, in Western countries, it is becoming increasingly popular as a remedy for fatigue and asthenia. This review provides an update on current research pertaining to ginseng and its isolated compounds, namely, ginsenosides and polysaccharides. The primary focus is on three crucial pharmacological activities, namely, immunomodulation, anti-inflammatory, and anti-cancer effects. The review encompasses studies on both isolated compounds and various ginseng extracts obtained from the root, leaves, and berries. MDPI 2023-05-03 /pmc/articles/PMC10180039/ /pubmed/37175273 http://dx.doi.org/10.3390/molecules28093863 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Valdés-González, Jose Antonio
Sánchez, Marta
Moratilla-Rivera, Ignacio
Iglesias, Irene
Gómez-Serranillos, María Pilar
Immunomodulatory, Anti-Inflammatory, and Anti-Cancer Properties of Ginseng: A Pharmacological Update
title Immunomodulatory, Anti-Inflammatory, and Anti-Cancer Properties of Ginseng: A Pharmacological Update
title_full Immunomodulatory, Anti-Inflammatory, and Anti-Cancer Properties of Ginseng: A Pharmacological Update
title_fullStr Immunomodulatory, Anti-Inflammatory, and Anti-Cancer Properties of Ginseng: A Pharmacological Update
title_full_unstemmed Immunomodulatory, Anti-Inflammatory, and Anti-Cancer Properties of Ginseng: A Pharmacological Update
title_short Immunomodulatory, Anti-Inflammatory, and Anti-Cancer Properties of Ginseng: A Pharmacological Update
title_sort immunomodulatory, anti-inflammatory, and anti-cancer properties of ginseng: a pharmacological update
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10180039/
https://www.ncbi.nlm.nih.gov/pubmed/37175273
http://dx.doi.org/10.3390/molecules28093863
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