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17-β-Estradiol—β-Cyclodextrin Complex as Solid: Synthesis, Structural and Physicochemical Characterization
17-β-estradiol (EST) is the most potent form of naturally occurring estrogens; therefore, it has found a wide pharmaceutical application. The major problem associated with the use of EST is its very low water solubility, resulting in poor oral bioavailability. To overcome this drawback, a complexati...
Autores principales: | Mazurek, Anna Helena, Szeleszczuk, Łukasz, Bethanis, Kostas, Christoforides, Elias, Dudek, Marta Katarzyna, Zielińska-Pisklak, Monika, Pisklak, Dariusz Maciej |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10180119/ https://www.ncbi.nlm.nih.gov/pubmed/37175157 http://dx.doi.org/10.3390/molecules28093747 |
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