Trimethylamine N-Oxide (TMAO) Inducing Endothelial Injury: UPLC-MS/MS-Based Quantification and the Activation of Cathepsin B-Mediated NLRP3 Inflammasome

TMAO is a new risk biomarker for cardiovascular disease. With trimethylammonium as its main chemical skeleton, TMAO is structurally similar to many endogenous metabolites, such as acetylcholine, carnitine, phosphorylcholine, etc. The mechanism of TMAO on the pathological process of CVD is still uncl...

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Detalles Bibliográficos
Autores principales: Lei, Dongyu, Yu, Wenbo, Liu, Yi, Jiang, Yujie, Li, Xiaohui, Lv, Jing, Li, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10180140/
https://www.ncbi.nlm.nih.gov/pubmed/37175227
http://dx.doi.org/10.3390/molecules28093817

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10180140/
https://www.ncbi.nlm.nih.gov/pubmed/37175227
http://dx.doi.org/10.3390/molecules28093817

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