Cargando…

D-Pinitol Improved Glucose Metabolism and Inhibited Bone Loss in Mice with Diabetic Osteoporosis

Diabetic osteoporosis (DO) has been increasingly recognized as an important complication of diabetes. D-pinitol, a natural compound found in various legumes, is known for its anti-diabetic function, but its effect on DO has not been investigated. Two doses of pinitol (50 and 100 mg/kg Bw/d) were adm...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Xinxin, Koyama, Tomoyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10180393/ https://www.ncbi.nlm.nih.gov/pubmed/37175278 http://dx.doi.org/10.3390/molecules28093870

Ejemplares similares

Bacterial volatile ammonia regulates the consumption sequence of d-pinitol and d-glucose in a fungus associated with an invasive bark beetle
por: Zhou, Fangyuan, et al.
Publicado: (2017)

D-Pinitol—Active Natural Product from Carob with Notable Insulin Regulation
por: Azab, Abdullatif
Publicado: (2022)

D-Pinitol treatment induced the apoptosis in human leukemia MOLT-4 cells by improved apoptotic signaling pathway
por: Yao, Xiangmei, et al.
Publicado: (2020)

Pharmacokinetics and Endocrine Effects of an Oral Dose of D-Pinitol in Human Fasting Healthy Volunteers
por: Navarro, Juan A., et al.
Publicado: (2022)

D-Pinitol Content and Antioxidant and Antidiabetic Activities of Five Bougainvillea spectabilis Willd. Cultivars
por: Abo-Elghiet, Fatma, et al.
Publicado: (2023)

Integrated proteomics and metabolomics analysis of D-pinitol function during hippocampal damage in streptozocin-induced aging-accelerated mice
por: Li, Xiaoxia, et al.
Publicado: (2023)

The effects of metformin and alendronate in attenuating bone loss and improving glucose metabolism in diabetes mellitus mice
por: Zhou, Qiyun, et al.
Publicado: (2022)

Activation of eNOS by D-pinitol Induces an Endothelium-Dependent Vasodilatation in Mouse Mesenteric Artery
por: Moreira, Luciana N., et al.
Publicado: (2018)

Endocrine and Metabolic Impact of Oral Ingestion of a Carob-Pod-Derived Natural-Syrup-Containing D-Pinitol: Potential Use as a Novel Sweetener in Diabetes
por: Navarro, Juan A., et al.
Publicado: (2022)

Novel insights into D-Pinitol based therapies: a link between tau hyperphosphorylation and insulin resistance
por: Medina-Vera, Dina, et al.
Publicado: (2023)

Water Deficit Elicits a Transcriptional Response of Genes Governing d-pinitol Biosynthesis in Soybean (Glycine max)
por: Dumschott, Kathryn, et al.
Publicado: (2019)

Symbiotic microbes aid host adaptation by metabolizing a deterrent host pine carbohydrate d-pinitol in a beetle-fungus invasive complex
por: Liu, Fanghua, et al.
Publicado: (2022)

Activation of PI3K/Akt Signaling Pathway in Rat Hypothalamus Induced by an Acute Oral Administration of D-Pinitol
por: Medina-Vera, Dina, et al.
Publicado: (2021)

D-pinitol Inhibits Prostate Cancer Metastasis through Inhibition of αVβ3 Integrin by Modulating FAK, c-Src and NF-κB Pathways
por: Lin, Tien-Huang, et al.
Publicado: (2013)

Bone Loss in Diabetes: Use of Antidiabetic Thiazolidinediones and Secondary Osteoporosis
por: Lecka-Czernik, Beata
Publicado: (2010)

D-Pinitol alleviates cyclosporine A-induced renal tubulointerstitial fibrosis via activating Sirt1 and Nrf2 antioxidant pathways
por: Koh, Eun Sil, et al.
Publicado: (2018)

d‐Pinitol promotes tau dephosphorylation through a cyclin‐dependent kinase 5 regulation mechanism: A new potential approach for tauopathies?
por: Medina‐Vera, Dina, et al.
Publicado: (2022)

Delphinidin, One of the Major Anthocyanidins, Prevents Bone Loss through the Inhibition of Excessive Osteoclastogenesis in Osteoporosis Model Mice
por: Moriwaki, Sawako, et al.
Publicado: (2014)

Protective Effect of Pinitol Against Inflammatory Mediators of Rheumatoid Arthritis via Inhibition of Protein Tyrosine Phosphatase Non-Receptor Type 22 (PTPN22)
por: Zheng, Kewen, et al.
Publicado: (2017)

D-Pinitol from Ceratonia siliqua Is an Orally Active Natural Inositol That Reduces Pancreas Insulin Secretion and Increases Circulating Ghrelin Levels in Wistar Rats
por: Navarro, Juan A., et al.
Publicado: (2020)

Prevention of Bone Loss in a Model of Postmenopausal Osteoporosis through Adrenomedullin Inhibition
por: Martínez-Herrero, Sonia, et al.
Publicado: (2016)

Obesity, osteoporosis and bone metabolism
por: Gkastaris, Konstantinos, et al.
Publicado: (2020)

Anti-Alzheimer Potential of a New (+)-Pinitol Glycoside Isolated from Tamarindus indica Pulp: In Vivo and In Silico Evaluations
por: Mohamed, Esraa M., et al.
Publicado: (2023)

Dried Plum’s Unique Capacity to Reverse Bone Loss and Alter Bone Metabolism in Postmenopausal Osteoporosis Model
por: Rendina, Elizabeth, et al.
Publicado: (2013)

The Preventive Effects of Probiotic Prevotella histicola on the Bone Loss of Mice with Ovariectomy-Mediated Osteoporosis
por: Zhang, Yuan-Wei, et al.
Publicado: (2023)

PREVALENCE OF OSTEOPOROSIS AND HYPOVITAMINOSIS D AT SIRIRAJ METABOLIC BONE DISEASE CLINIC
por: UNNANUNTANA, AASIS, et al.
Publicado: (2017)

1-deoxynojirimycin inhibits glucose absorption and accelerates glucose metabolism in streptozotocin-induced diabetic mice
por: Li, You-Gui, et al.
Publicado: (2013)

Fecal microbiota transplantation ameliorates bone loss in mice with ovariectomy-induced osteoporosis via modulating gut microbiota and metabolic function
por: Zhang, Yuan-Wei, et al.
Publicado: (2022)

Cyclophilin D Knock-Out Mice Show Enhanced Resistance to Osteoporosis and to Metabolic Changes Observed in Aging Bone
por: Shum, Laura C., et al.
Publicado: (2016)

Oral Administration of Quercetin or Its Derivatives Inhibit Bone Loss in Animal Model of Osteoporosis
por: Huang, Yue-Yue, et al.
Publicado: (2020)

Secondary Osteoporosis and Metabolic Bone Diseases
por: Sobh, Mahmoud M., et al.
Publicado: (2022)

Berberine Improves Glucose Metabolism in Diabetic Rats by Inhibition of Hepatic Gluconeogenesis
por: Xia, Xuan, et al.
Publicado: (2011)

Dolichos Lablab Linné Inhibits Bone Density Loss and Promotes Bone Union in Senile Osteoporosis through Osteogenesis
por: Kim, Minsun, et al.
Publicado: (2023)

The Ethanol Extracts of Osmanthus fragrans Leaves Ameliorate the Bone Loss via the Inhibition of Osteoclastogenesis in Osteoporosis
por: Seo, Yo-Seob, et al.
Publicado: (2023)

Kanamycin inhibits daidzein metabolism and abilities of the metabolites to prevent bone loss in ovariectomized mice
por: Katsumata, Shin-ichi, et al.
Publicado: (2016)

Bovine Colostrum Supplementation Improves Bone Metabolism in an Osteoporosis-Induced Animal Model
por: Kydonaki, Eirini K., et al.
Publicado: (2021)

Cooperative Anti-Diabetic Effects of Deoxynojirimycin-Polysaccharide by Inhibiting Glucose Absorption and Modulating Glucose Metabolism in Streptozotocin-Induced Diabetic Mice
por: Li, You-Gui, et al.
Publicado: (2013)

The Roles of Epigenetics Regulation in Bone Metabolism and Osteoporosis
por: Xu, Fei, et al.
Publicado: (2021)

Osteoporosis and bone metabolism in patients with Klinefelter syndrome
por: Grande, Giuseppe, et al.
Publicado: (2023)

Osteoblast-intrinsic defect in glucose metabolism impairs bone formation in type II diabetic mice
por: Song, Fangfang, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_331he5mlagtdpc81psia92d2ea