The Influence of APOE Genotype, DHA, and Flavanol Intervention on Brain DHA and Lipidomics Profile in Aged Transgenic Mice

The apolipoprotein E4 (APOE4) genotype is predictive of Alzheimer’s disease (AD). The brain is highly enriched with the omega-3 polyunsaturated fatty acid (n3-PUFA), docosahexaenoic acid (DHA). DHA’s metabolism is defective in APOE4 carriers. Flavanol intake can play a role in modulating DHA levels....

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Detalles Bibliográficos
Autores principales: Martinsen, Anneloes, Saleh, Rasha N. M., Chouinard-Watkins, Raphael, Bazinet, Richard, Harden, Glenn, Dick, James, Tejera, Noemi, Pontifex, Matthew G., Vauzour, David, Minihane, Anne-Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10180974/
https://www.ncbi.nlm.nih.gov/pubmed/37432149
http://dx.doi.org/10.3390/nu15092032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10180974/
https://www.ncbi.nlm.nih.gov/pubmed/37432149
http://dx.doi.org/10.3390/nu15092032

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