Cargando…

Structures, Properties, and Bioengineering Applications of Alginates and Hyaluronic Acid

In recent years, polymeric materials have been used in a wide range of applications in a variety of fields. In particular, in the field of bioengineering, the use of natural biomaterials offers a possible new avenue for the development of products with better biocompatibility, biodegradability, and...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Shuping, Dong, Jiayu, Pan, Renxue, Xu, Zhenyang, Li, Mengyuan, Zang, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10181120/
https://www.ncbi.nlm.nih.gov/pubmed/37177293
http://dx.doi.org/10.3390/polym15092149
_version_ 1785041496830902272
author Zhang, Shuping
Dong, Jiayu
Pan, Renxue
Xu, Zhenyang
Li, Mengyuan
Zang, Rui
author_facet Zhang, Shuping
Dong, Jiayu
Pan, Renxue
Xu, Zhenyang
Li, Mengyuan
Zang, Rui
author_sort Zhang, Shuping
collection PubMed
description In recent years, polymeric materials have been used in a wide range of applications in a variety of fields. In particular, in the field of bioengineering, the use of natural biomaterials offers a possible new avenue for the development of products with better biocompatibility, biodegradability, and non-toxicity. This paper reviews the structural and physicochemical properties of alginate and hyaluronic acid, as well as the applications of the modified cross-linked derivatives in tissue engineering and drug delivery. This paper summarizes the application of alginate and hyaluronic acid in bone tissue engineering, wound dressings, and drug carriers. We provide some ideas on how to replace or combine alginate-based composites with hyaluronic-acid-based composites in tissue engineering and drug delivery to achieve better eco-economic value.
format Online
Article
Text
id pubmed-10181120
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-101811202023-05-13 Structures, Properties, and Bioengineering Applications of Alginates and Hyaluronic Acid Zhang, Shuping Dong, Jiayu Pan, Renxue Xu, Zhenyang Li, Mengyuan Zang, Rui Polymers (Basel) Review In recent years, polymeric materials have been used in a wide range of applications in a variety of fields. In particular, in the field of bioengineering, the use of natural biomaterials offers a possible new avenue for the development of products with better biocompatibility, biodegradability, and non-toxicity. This paper reviews the structural and physicochemical properties of alginate and hyaluronic acid, as well as the applications of the modified cross-linked derivatives in tissue engineering and drug delivery. This paper summarizes the application of alginate and hyaluronic acid in bone tissue engineering, wound dressings, and drug carriers. We provide some ideas on how to replace or combine alginate-based composites with hyaluronic-acid-based composites in tissue engineering and drug delivery to achieve better eco-economic value. MDPI 2023-04-30 /pmc/articles/PMC10181120/ /pubmed/37177293 http://dx.doi.org/10.3390/polym15092149 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Zhang, Shuping
Dong, Jiayu
Pan, Renxue
Xu, Zhenyang
Li, Mengyuan
Zang, Rui
Structures, Properties, and Bioengineering Applications of Alginates and Hyaluronic Acid
title Structures, Properties, and Bioengineering Applications of Alginates and Hyaluronic Acid
title_full Structures, Properties, and Bioengineering Applications of Alginates and Hyaluronic Acid
title_fullStr Structures, Properties, and Bioengineering Applications of Alginates and Hyaluronic Acid
title_full_unstemmed Structures, Properties, and Bioengineering Applications of Alginates and Hyaluronic Acid
title_short Structures, Properties, and Bioengineering Applications of Alginates and Hyaluronic Acid
title_sort structures, properties, and bioengineering applications of alginates and hyaluronic acid
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10181120/
https://www.ncbi.nlm.nih.gov/pubmed/37177293
http://dx.doi.org/10.3390/polym15092149
work_keys_str_mv AT zhangshuping structurespropertiesandbioengineeringapplicationsofalginatesandhyaluronicacid
AT dongjiayu structurespropertiesandbioengineeringapplicationsofalginatesandhyaluronicacid
AT panrenxue structurespropertiesandbioengineeringapplicationsofalginatesandhyaluronicacid
AT xuzhenyang structurespropertiesandbioengineeringapplicationsofalginatesandhyaluronicacid
AT limengyuan structurespropertiesandbioengineeringapplicationsofalginatesandhyaluronicacid
AT zangrui structurespropertiesandbioengineeringapplicationsofalginatesandhyaluronicacid