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Optimization of a Mucoadhesive Vaginal Gel Containing Clotrimazole Using a D-Optimal Experimental Design and Multivariate Analysis

The aim of this study was to develop a suitable clotrimazole (CLT)-loaded mucoadhesive vaginal gel (CLT-MVG) for topical applications in vaginal candidiasis. Ten CLT-MVG formulations were prepared, consisting of mixtures of acid polyacrylic (Carbopol 940) and polyethene oxides, Sentry Polyox WSRN 11...

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Detalles Bibliográficos
Autores principales:	Dinte, Elena, Iovanov, Rares Iuliu, Bodoki, Andreea Elena, Colosi, Ioana Alina, Colosi, Horatiu Alexandru, Tosa, Nicoleta, Vostinaru, Oliviu, Tomuta, Ioan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10181139/ https://www.ncbi.nlm.nih.gov/pubmed/37177171 http://dx.doi.org/10.3390/polym15092023

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