Obesity impairs cardiolipin-dependent mitophagy and therapeutic intercellular mitochondrial transfer ability of mesenchymal stem cells

Mesenchymal stem cell (MSC) transplantation alleviates metabolic defects in diseased recipient cells by intercellular mitochondrial transport (IMT). However, the effect of host metabolic conditions on IMT and thereby on the therapeutic efficacy of MSCs has largely remained unexplored. Here we found...

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Detalles Bibliográficos
Autores principales: Sagar, Shakti, Faizan, Md Imam, Chaudhary, Nisha, Singh, Vandana, Singh, Praveen, Gheware, Atish, Sharma, Khushboo, Azmi, Iqbal, Singh, Vijay Pal, Kharya, Gaurav, Mabalirajan, Ulaganathan, Agrawal, Anurag, Ahmad, Tanveer, Sinha Roy, Soumya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10181927/
https://www.ncbi.nlm.nih.gov/pubmed/37173333
http://dx.doi.org/10.1038/s41419-023-05810-3

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