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Unusual presentation of acquired thrombotic thrombocytopenic purpura (TTP) versus catastrophic antiphospholipid syndrome in a patient with Moya‐Moya disease, case report, and literature review

Coincidences in medicine are not so common. We are presenting a case of a patient diagnosed with Moya‐Moya disease and antiphospholipid syndrome (APS) who presented with clinical and laboratory characteristics of catastrophic APS versus TTP. The diagnosis was a challenge because characteristics were...

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Autores principales: Guevara‐Rodriguez, Nehemias, Marmanillo‐Mendoza, Gabriela, Castelar, Jorge, Ciobanu, Camelia, Fulger, Ilmana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182009/
https://www.ncbi.nlm.nih.gov/pubmed/37192853
http://dx.doi.org/10.1002/ccr3.7317
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author Guevara‐Rodriguez, Nehemias
Marmanillo‐Mendoza, Gabriela
Castelar, Jorge
Ciobanu, Camelia
Fulger, Ilmana
author_facet Guevara‐Rodriguez, Nehemias
Marmanillo‐Mendoza, Gabriela
Castelar, Jorge
Ciobanu, Camelia
Fulger, Ilmana
author_sort Guevara‐Rodriguez, Nehemias
collection PubMed
description Coincidences in medicine are not so common. We are presenting a case of a patient diagnosed with Moya‐Moya disease and antiphospholipid syndrome (APS) who presented with clinical and laboratory characteristics of catastrophic APS versus TTP. The diagnosis was a challenge because characteristics were overlapping. Nevertheless, a decision to treat the patient for TTP was made with afterward improvement. MMD has been associated with multiple immune disorders; however, only one case of acquired thrombotic thrombocytopenic purpura has been documented in association with this disease. None has been associated with catastrophic antiphospholipid syndrome. We are presenting a challenging case where all these three medical conditions were present at the same time.
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spelling pubmed-101820092023-05-14 Unusual presentation of acquired thrombotic thrombocytopenic purpura (TTP) versus catastrophic antiphospholipid syndrome in a patient with Moya‐Moya disease, case report, and literature review Guevara‐Rodriguez, Nehemias Marmanillo‐Mendoza, Gabriela Castelar, Jorge Ciobanu, Camelia Fulger, Ilmana Clin Case Rep Case Report Coincidences in medicine are not so common. We are presenting a case of a patient diagnosed with Moya‐Moya disease and antiphospholipid syndrome (APS) who presented with clinical and laboratory characteristics of catastrophic APS versus TTP. The diagnosis was a challenge because characteristics were overlapping. Nevertheless, a decision to treat the patient for TTP was made with afterward improvement. MMD has been associated with multiple immune disorders; however, only one case of acquired thrombotic thrombocytopenic purpura has been documented in association with this disease. None has been associated with catastrophic antiphospholipid syndrome. We are presenting a challenging case where all these three medical conditions were present at the same time. John Wiley and Sons Inc. 2023-05-12 /pmc/articles/PMC10182009/ /pubmed/37192853 http://dx.doi.org/10.1002/ccr3.7317 Text en © 2023 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Report
Guevara‐Rodriguez, Nehemias
Marmanillo‐Mendoza, Gabriela
Castelar, Jorge
Ciobanu, Camelia
Fulger, Ilmana
Unusual presentation of acquired thrombotic thrombocytopenic purpura (TTP) versus catastrophic antiphospholipid syndrome in a patient with Moya‐Moya disease, case report, and literature review
title Unusual presentation of acquired thrombotic thrombocytopenic purpura (TTP) versus catastrophic antiphospholipid syndrome in a patient with Moya‐Moya disease, case report, and literature review
title_full Unusual presentation of acquired thrombotic thrombocytopenic purpura (TTP) versus catastrophic antiphospholipid syndrome in a patient with Moya‐Moya disease, case report, and literature review
title_fullStr Unusual presentation of acquired thrombotic thrombocytopenic purpura (TTP) versus catastrophic antiphospholipid syndrome in a patient with Moya‐Moya disease, case report, and literature review
title_full_unstemmed Unusual presentation of acquired thrombotic thrombocytopenic purpura (TTP) versus catastrophic antiphospholipid syndrome in a patient with Moya‐Moya disease, case report, and literature review
title_short Unusual presentation of acquired thrombotic thrombocytopenic purpura (TTP) versus catastrophic antiphospholipid syndrome in a patient with Moya‐Moya disease, case report, and literature review
title_sort unusual presentation of acquired thrombotic thrombocytopenic purpura (ttp) versus catastrophic antiphospholipid syndrome in a patient with moya‐moya disease, case report, and literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182009/
https://www.ncbi.nlm.nih.gov/pubmed/37192853
http://dx.doi.org/10.1002/ccr3.7317
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