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Cross-disorder genetic analysis of immune diseases reveals distinct gene associations that converge on common pathways

Genome-wide association studies (GWAS) have mapped thousands of susceptibility loci associated with immune-mediated diseases. To assess the extent of the genetic sharing across nine immune-mediated diseases we apply genomic structural equation modelling to GWAS data from European populations. We ide...

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Detalles Bibliográficos
Autores principales:	Demela, Pietro, Pirastu, Nicola, Soskic, Blagoje
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182075/ https://www.ncbi.nlm.nih.gov/pubmed/37173304 http://dx.doi.org/10.1038/s41467-023-38389-6

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