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Health-related quality of life among thalassemia patients in Bangladesh using the SF-36 questionnaire

Thalassemia is one of the most common autosomal recessive hereditary blood disorders worldwide, especially in developing countries, including Bangladesh. Thus, this study aimed to determine HRQoL and its determinants of thalassemia patients (TP) in Bangladesh. A cross-sectional survey was performed...

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Autores principales: Hossain, Md Jubayer, Islam, Md Wahidul, Munni, Ummi Rukaiya, Gulshan, Rubaiya, Mukta, Sumaiya Akter, Miah, Md Sharif, Sultana, Sabia, Karmakar, Mousumi, Ferdous, Jannatul, Islam, Mohammad Ariful
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182078/
https://www.ncbi.nlm.nih.gov/pubmed/37173392
http://dx.doi.org/10.1038/s41598-023-34205-9
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author Hossain, Md Jubayer
Islam, Md Wahidul
Munni, Ummi Rukaiya
Gulshan, Rubaiya
Mukta, Sumaiya Akter
Miah, Md Sharif
Sultana, Sabia
Karmakar, Mousumi
Ferdous, Jannatul
Islam, Mohammad Ariful
author_facet Hossain, Md Jubayer
Islam, Md Wahidul
Munni, Ummi Rukaiya
Gulshan, Rubaiya
Mukta, Sumaiya Akter
Miah, Md Sharif
Sultana, Sabia
Karmakar, Mousumi
Ferdous, Jannatul
Islam, Mohammad Ariful
author_sort Hossain, Md Jubayer
collection PubMed
description Thalassemia is one of the most common autosomal recessive hereditary blood disorders worldwide, especially in developing countries, including Bangladesh. Thus, this study aimed to determine HRQoL and its determinants of thalassemia patients (TP) in Bangladesh. A cross-sectional survey was performed on 356 randomly selected thalassemia patients. Participants were invited to face-to-face interviews. Descriptive statistics (frequencies and percentages), independent t-test, ANOVA, and multivariate (linear and logistic regression) analysis was performed to analyze the data. Our demographic data showed that among 356 patients, 54% and 46% were male and female, respectively, with an average age of 19.75 (SD = 8.02) years. Most were transfusion-dependent (91%), 26% had comorbidities, and 52% were from low-income families. In the case of HRQoL, male patients showed significantly higher scores of bodily pains and physical health summaries than female patients. Lower income, high blood transfusion status, disease severity, comorbidities, and medical expenses (p < 0.05; CI 95%) are significantly associated with lower SF-36 scores. This study found an association between lower income, blood transfusion, disease severity, comorbidities, as well as medical expenses, and the deterioration of HRQoL among TP. Male patients experienced poorer HRQoL than females. National action plans are required to guarantee the holistic welfare of thalassemia patients.
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spelling pubmed-101820782023-05-14 Health-related quality of life among thalassemia patients in Bangladesh using the SF-36 questionnaire Hossain, Md Jubayer Islam, Md Wahidul Munni, Ummi Rukaiya Gulshan, Rubaiya Mukta, Sumaiya Akter Miah, Md Sharif Sultana, Sabia Karmakar, Mousumi Ferdous, Jannatul Islam, Mohammad Ariful Sci Rep Article Thalassemia is one of the most common autosomal recessive hereditary blood disorders worldwide, especially in developing countries, including Bangladesh. Thus, this study aimed to determine HRQoL and its determinants of thalassemia patients (TP) in Bangladesh. A cross-sectional survey was performed on 356 randomly selected thalassemia patients. Participants were invited to face-to-face interviews. Descriptive statistics (frequencies and percentages), independent t-test, ANOVA, and multivariate (linear and logistic regression) analysis was performed to analyze the data. Our demographic data showed that among 356 patients, 54% and 46% were male and female, respectively, with an average age of 19.75 (SD = 8.02) years. Most were transfusion-dependent (91%), 26% had comorbidities, and 52% were from low-income families. In the case of HRQoL, male patients showed significantly higher scores of bodily pains and physical health summaries than female patients. Lower income, high blood transfusion status, disease severity, comorbidities, and medical expenses (p < 0.05; CI 95%) are significantly associated with lower SF-36 scores. This study found an association between lower income, blood transfusion, disease severity, comorbidities, as well as medical expenses, and the deterioration of HRQoL among TP. Male patients experienced poorer HRQoL than females. National action plans are required to guarantee the holistic welfare of thalassemia patients. Nature Publishing Group UK 2023-05-12 /pmc/articles/PMC10182078/ /pubmed/37173392 http://dx.doi.org/10.1038/s41598-023-34205-9 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Hossain, Md Jubayer
Islam, Md Wahidul
Munni, Ummi Rukaiya
Gulshan, Rubaiya
Mukta, Sumaiya Akter
Miah, Md Sharif
Sultana, Sabia
Karmakar, Mousumi
Ferdous, Jannatul
Islam, Mohammad Ariful
Health-related quality of life among thalassemia patients in Bangladesh using the SF-36 questionnaire
title Health-related quality of life among thalassemia patients in Bangladesh using the SF-36 questionnaire
title_full Health-related quality of life among thalassemia patients in Bangladesh using the SF-36 questionnaire
title_fullStr Health-related quality of life among thalassemia patients in Bangladesh using the SF-36 questionnaire
title_full_unstemmed Health-related quality of life among thalassemia patients in Bangladesh using the SF-36 questionnaire
title_short Health-related quality of life among thalassemia patients in Bangladesh using the SF-36 questionnaire
title_sort health-related quality of life among thalassemia patients in bangladesh using the sf-36 questionnaire
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182078/
https://www.ncbi.nlm.nih.gov/pubmed/37173392
http://dx.doi.org/10.1038/s41598-023-34205-9
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